The M2 Macrophage

Röszer, Tamás

The M2 Macrophage Tamás Röszer - Cham Springer Nature Switzerland 2020 - 1 recurso en línea (399 páginas)

Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling.

978-3-030-50480-9


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QR185 / .M6 2020 EB