Epidemiology of the Infected Total Knee Arthroplasty: Incidence, Causes and the Burden of Disease -- Microbiological concepts of the infected total knee arthroplasty -- Preoperative optimization to prevent an infected total knee arthroplasty: Host factors -- Depilation and skin preparation to prevent an infected total knee arthroplasty -- Antibiotic prophylaxis to prevent infection in total knee arthroplasty -- Preoperative screening and eradication of infection -- Clinical diagnosis of the infected total knee arthroplasty -- Diagnosis by imaging of the infected total knee arthroplasty -- Serological markers of infection in the infected total knee arthroplasty -- The role of knee aspiration in the infected total knee arthroplasty -- Polymerase chain reaction (PCR) in the infected total knee arthroplasty -- Histological diagnosis in the infected total knee arthroplasty -- Intra-operative Cultures for the Suspected Total Knee Arthroplasty Infection -- Sonication of removed implants in the infected total knee arthroplasty -- Antibiotic suppression in the infected total knee arthroplasty -- Arthroscopic debridement of infected total knee arthroplasty -- Open debridement and polyethylene exchange (ODPE) in the infected total knee arthroplasty -- One-stage revision arthroplasty in the infected total knee arthroplasty -- Two-stage revision of infected total knee arthroplasty -- Knee arthrodesis in the infected total knee arthroplasty -- Above Knee Amputation in the Treatment of Failed Septic Total Knee Arthroplasty.

This book is structured in a way that guides the reader from prevention through to diagnosis and then treatment of infection following total knee arthroplasty, in each case providing state of the art information on available techniques and procedures. The section on the crucial preventive measures include guidance on preoperative optimization and skin preparation, antibiotic prophylaxis, and preoperative microbiological screening. All relevant aspects of diagnosis of infection are considered in detail, and the treatment-related section includes chapters on antibiotic suppression, arthroscopic lavage, open debridement with polyethylene exchange, one- and two-stage revision arthroplasty, and knee arthrodesis as a salvage procedure. Readers will also find clear instruction on how to proceed when all attempts to eradicate infection fail. In reflecting the latest knowledge and practice in this rapidly advancing field, the book will be an asset to all who are involved in the care of these patients. .