I Introduction to Diffuse Parenchimal Lung Disease -- 1 Diffuse Parenchymal Lung Disease: A Clinical Overview -- 2 Radiologic-pathologic Correlations in Diffuse Parenchymal Lung Disease -- 3 Multidisciplinary discussion in Diffuse Parenchymal Lung Disease -- II Transbronchial cryobiopsy -- 4 Cryobiopsy: Physics -- 5 Cryobiopsy: How it Happened -- 6 Technique and equipment in Transbronchial Cryobiopsy -- 7 Complications in Transbronchial Cryobiopsy -- 8 Immunohystochemistry and Molecular Biology in Transbronchial Cryobiopsy -- III Clinical role of Transbronchial Cryobiopsy -- 9 The Diagnostic Yield of Transbronchial Cryobiopsy -- 10 Clinical Meaning of Transbronchial Cryobiopsy -- 11 Pathologic considerations in Transbronchial Cryobiopsy -- 12 Future perspectives for Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease -- IV Case series -- 13 Idiopahic Pulmonary Fibrosis -- 14 Chronic hypersensitivity pneumonitis -- 15 Other granulomatoses -- 16 Nonspecific interstitial pneumonia -- 17 Collagen vascular diseases -- 18 Smoking related ILDs -- 19 Lymphangioleiomyomatosis -- 20 Pleuroparenchymal fibroelastosis -- 21 Acute lung injury -- 22 Neoplasms -- 23 Rarities.

This book presents both theoretical and practical aspects of transbronchial cryobiopsy, a new diagnostic technique for the detection of diffuse parenchymal lung disease that is attracting great interest in the scientific community. In the context of a multidisciplinary discussion, comprising radiologic-pathologic correlations, the authors examine the technical and safety issues - such as equipment, endoscopic setting, anesthesiologic approaches and bleeding control - on one hand, and the diagnostic yield and clinical meaning on the other. The volume offers several case studies - including idiopathic pulmonary fibrosis, granulomatous disorders, interstitial pneumonias, rare lung disseminated tumors- that illustrate the high diagnostic yield and safety of this innovative technique. The book appeals to a wide readership, including residents, pulmonologists with expertise in diffuse parenchymal lung diseases, interventional pulmonologists, thoracic radiologists, pathologists, anesthesiologists, internists and rheumatologists.