Bleeding Disorders and Heavy Menstrual Bleeding
Front Matter
Pages 1-1
Evaluation of the Adolescent with Heavy Menstrual Bleeding
Ayesha Zia, May Lau
Pages 3-11
Screening Tools for Evaluating the Bleeding Adolescent
Kalinda Woods, Sue Kearney
Pages 13-27
von Willebrand Disease
Trinh Nguyen, Lakshmi V. Srivaths
Pages 29-42
Hemophilia Carriers
Allison P. Wheeler, Robert F. Sidonio
Pages 43-50
Rare Coagulation Factor Deficiencies
Shilpa Jain, Suchitra S. Acharya
Pages 51-60
Platelet Disorders in the Adolescent Female
Deepti Warad, Meera Chitlur, Claire Philipp
Pages 61-78
Fibrinolytic Pathway Disorders
Shveta Gupta, Sweta Gupta
Pages 79-87
Hypermobility Syndromes in Heavy Menstrual Bleeding
Genevieve Moyer, Patricia Huguelet, Pamela Trapane
Pages 89-98
Complications of Heavy Menstrual Bleeding in Adolescents
Irmel A. Ayala, Enitan Adegite
Pages 99-108
Hormonal Therapy for Heavy Menstrual Bleeding
Maureen K. Baldwin, Jennifer L. Bercaw-Pratt
Pages 109-118
Hemostatic Therapies for Heavy Menstrual Bleeding
Sanjay P. Ahuja, Michael Recht, Barbara Konkle
Pages 119-127
Quality of Life in Female Adolescents with Bleeding Disorders
Anjali Pawar, Roshni Kulkarni
Pages 129-137
Thromboembolism in the Adolescent Female
Front Matter
Pages 139-139
Prevalence and Risk Factors of Adolescent Venous Thromboembolism
Arash Mahjerin, Julie Jaffray, Brian Branchford
Pages 141-152
Diagnosis, Prevention, and Management of Venous Thromboembolism in the Adolescent Female
Lauren E. Amos, Mukta Sharma, Shannon L. Carpenter
Pages 153-161
Thrombophilia and Hormonal Therapy in Adolescents
Shannon M. Bates, Tazim Dowlut-McElroy, Kelley McLean
Pages 163-174
Heavy Menstrual Bleeding and Anticoagulation
Angela C. Weyand, Janice M. Staber
Pages 175-182
Anemia in the Adolescent Female
Front Matter
Pages 183-183
Iron Deficiency Anemia
Amanda E. Jacobson-Kelly, Ruchika Sharma, Jacquelyn M. Powers
Pages 185-194
Vitamin B12 Deficiency
Jennifer Davila, Maria C. Velez-Yanguas
Pages 195-201
Hemoglobinopathies in the Adolescent Female
Front Matter
Pages 203-203
Thalassemia Disorders in the Adolescent Female
Stephanie A. Fritch Lilla, Sylvia T. Singer, Elliott P. Vichinsky
Pages 205-216
Sickle Cell Disease in the Adolescent Female
Nelda Itzep, Vivien Sheehan
Pages 217-225
Immune Hematology in the Adolescent Female
Front Matter
Pages 227-227
Immune Thrombocytopenia in Adolescents
Anna Griffith, Alice D. Ma
Pages 229-236
Autoimmune Hemolytic Anemia in Adolescent Females
Taylor Olmsted Kim, James B. Bussel
Pages 237-252
Evans Syndrome in the Adolescent Female
Amanda B. Grimes, Vicky R. Breakey
Pages 253-265
Antiphospholipid Syndrome
Neha Bhasin, Christine Knoll, Leslie M. Skeith
Pages 267-278
Thrombotic Microangiopathy in the Adolescent Female
Clay T. Cohen, Tammuella Chrisentery Singleton, Sarah E. Sartain
Pages 279-288
Bone Marrow Failure Disorders in the Adolescent Female
Front Matter
Pages 289-289
Bone Marrow Failure Disorders in the Adolescent Female
Ghadir S. Sasa, Adrianna Vlachos
Pages 291-307
Blood Disorders in the Pregnant Adolescent
Front Matter
Pages 309-309
Adolescent Pregnancy Complicated by Thrombosis
Candice M. Dersch, Peter A. Kouides
Pages 311-318
Bleeding Disorders in Pregnancy
Maissa Janbain, Peter A. Kouides
Pages 319-322

Adolescent females experience a variety of blood disorders that are often unique to this patient population. As they go through puberty, they are uniquely poised to encounter various bleeding and thrombotic disorders once they attain menarche, start to have menstrual bleeding, and require hormonal therapy. This may in turn lead to other medical conditions, such as anemia and iron deficiency. Pregnancy encountered by some adolescents can pose hematologic challenges specifically in regards to bleeding and thrombotic disorders. In addition, adolescent females are at risk to develop immune mediated hematologic disorders, such as immune thrombocytopenia, auto-immune hemolytic anemia, and thrombotic thrombocytopenic purpura, as well as vitamin deficiencies due to pernicious anemia. Sickle cell disease, thalassemia and bone marrow failure disorders in the adolescent female poses unique challenges that need to be addressed with special care and attention. Knowledge about these various blood disorders in adolescent females is crucial for the treating physician in order to accurately diagnose and optimally manage these teenagers. Otherwise, it can affect their overall health, causing hematologic and gynecologic issues, poor quality of life, neurocognitive impairments, and poor psycho-social development, all of which can lead to various complications immediately and into adulthood.

This book provides a comprehensive, state-of-the art overview of blood disorders in female adolescents. The text presents new data about bleeding disorders that affect the female adolescent, including bleeding disorders, thromboembolism, thrombophilia, anemia, sickle cell disease and thalassemia, disorders od hemostasis and thrombosis in pregnancy, immune hematology and bone marrow failure disorders; reviews our current understanding of these disorders; outlines recent research findings; and spotlights multi-disciplinary approaches, evaluation and treatment modalities to combat these blood disorders.

Written by experts in the field, Hematology in the Adolescent Female is a valuable resource for clinicians and practitioners who treat and manage female adolescents with blood disorders.