Overview of the Mechanical Circulatory Support
Front Matter
Pages 1-1
A History of Mechanical Circulatory Support
Shelley McKellar
Pages 3-17
A Personalized History of Rotary Blood Pumps
Richard Wampler
Pages 19-36
History of Pediatric Devices for Mechanical Circulatory Support
Kurt A. Dasse, Priscilla C. Petit
Pages 37-49
Overview of Mechanical Circulatory Support Devices and Concepts
Juan Marcano, Aladdein Mattar, Jeffrey A. Morgan
Pages 51-61
Physiology of Blood Pump Circulation in Heart Failure
Abhinav Saxena, Nir Uriel, Daniel Burkhoff
Pages 63-82
Engineering Requirements for Mechanical Circulatory Support Devices
J. Timothy Baldwin
Pages 83-90
Clinical Requirements for Mechanical Circulatory Support Devices
Neel K. Ranganath, Katherine G. Phillips, Nader Moazami
Pages 91-107
Engineering Perspectives for Mechanical Circulatory Support Devices
Kevin Bourque, Christopher Cotter, Charles Dague
Pages 109-127
Indications and Selection for Mechanical Circulatory Support
Front Matter
Pages 129-129
Patient Population and Selection Criteria for Mechanical Circulatory Support
Pavan Bhat, Randall C. Starling
Pages 131-139
Mechanical Circulatory Support Therapies: Right Timing and Prognosis Considerations
Felix Schoenrath, Evgenij Potapov
Pages 141-150
Perioperative Considerations in Left Ventricular Assist Device Placement
Ranjani Venkataramani, Michael Zhen-Yu Tong, Shiva Sale
Pages 151-169
Left Ventricular Assist Devices: Management and Surgical Techniques
Robert J. Steffen, Benjamin C. Sun
Pages 171-176
Mechanical Circulatory Support for Biventricular Failure: Patient Selection and Management Options
Kimberly N. Hong, Hao A. Tran, Victor Pretorius, Eric D. Adler
Pages 177-189
Status and Availability of a Total Artificial Heart
Katherine G. Phillips, Neel K. Ranganath, Nader Moazami
Pages 191-206
Extracorporeal Membrane Oxygenation Techniques and Modern Considerations
Aly El Banayosy
Pages 207-220
Less Invasive Extra-pericardial Placement (LIEPP) of LVAD
Areo Saffarzadeh, Pramod Bonde
Pages 221-227
Parameters of Physiologic and Non-physiologic Blood Flow
Front Matter
Pages 229-229
Pulsatile Mechanical Circulation, Physiology, and Pump Technology
Jack Copeland, Hannah Copeland
Pages 231-252
Pathophysiological Determinants Relevant in Blood Pump Control
Marianne Schmid Daners, Seraina Anne Dual
Pages 253-277
End-Organ Physiology Under Continuous-Flow Mechanical Circulatory Support
Egemen Tuzun
Pages 279-300
Quantification of Pulsatility During Mechanical Circulatory Support
Shigang Wang, Morgan K. Moroi, Akif Ündar
Pages 301-315
Pulsatility as an Option with Continuous-Flow Mechanical Circulatory Support Devices
Chelsea Lancaster, Michael A. Sobieski, Mark S. Slaughter, Steven Koenig
Pages 317-333
Current Technology and Methods
Front Matter
Pages 335-335
Implantable Continuous-Flow Blood Pump Technology and Features
Matthew L. Goodwin, Peter H. U. Lee, Nahush A. Mokadam
Pages 337-358
Partial Support with Mechanical Circulatory Support Devices
Jordan R. H. Hoffman, Joseph C. Cleveland Jr
Pages 359-377
Percutaneous Mechanical Circulatory Support Technologies
Jerry D. Estep
Pages 379-397
Computational Fluid Dynamics for Mechanical Circulatory Support Device Development
Roland Graefe, Lutz Pauli
Pages 399-427
Hemodynamic Modelling and Simulations for Mechanical Circulatory Support
Libera Fresiello, Krzysztof Zieliński
Pages 429-447
Options for Modeling and Simulations Used in Mechanical Circulatory Support Development
David J. Horvath, Kiyotaka Fukamachi, Jamshid H. Karimov
Pages 449-465
Evolving Technologies and Device Concepts
Front Matter
Pages 467-467
Emerging Continuous-Flow Blood Pump Technologies
Harveen K. Lamba, Jeffrey A. Morgan
Pages 469-480
The Development of Advanced Ventricular Assist Device as a Next Generation Ventricular Assist Device
Takuma Miyamoto, Jamshid H. Karimov, David J. Horvath, Nicole Byram, Kiyotaka Fukamachi
Pages 481-492
Cleveland Clinic Total Artificial Heart
Jamshid H. Karimov, David J. Horvath, Kiyotaka Fukamachi
Pages 493-504
The ReinVAD LVAD: Smart Technology to Enhance Long-Term Circulatory Support Therapy
Roland Graefe, Erika Minguez, Andreas Henseler, Reiner Körfer
Pages 505-533
EVAHEART 2 Left Ventricular Assist System: A Hemocompatible Centrifugal Pump with Physiological Pulsatility
Tadashi Motomura
Pages 535-544
A Novel Rotary Total Artificial Heart Using a Single Shuttling Impeller
Jeremy Glynn, Richard Wampler
Pages 545-554
New Mechanical Circulatory Device: TORVAD
Jeffrey Gohean, Richard Smalling
Pages 555-561
BiVACOR Total Artificial Heart
Daniel L. Timms, Frank Nestler
Pages 563-575
The Penn State Pediatric Total Artificial Heart
William J. Weiss, Raymond Newswanger, J. Brian Clark, Jenelle M. Izer
Pages 577-585
CorWave LVAD: Insight into Device Concept and Stage of Development
Carl Botterbusch, Trevor Snyder, Pier-Paolo Monticone, Louis de Lillers, Alexandra Schmidt, Charlotte Rasser
Pages 587-597
Progress on Total Artificial Heart for Pediatric Patients
Kiyotaka Fukamachi, Jamshid H. Karimov, Takuma Miyamoto
Pages 599-608
Progress on Wireless LVAD and Energy Sources for Mechanical Circulatory Systems
John Valdovinos, Jiheum Park, Joshua Smith, Pramod Bonde
Pages 609-620
Management Strategies and Limitations of MCS
Front Matter
Pages 621-621
Risk Factors for Mechanical Circulatory Support Use and Risk Assessment
Rajakrishnan Vijayakrishnan, Emma J. Birks
Pages 623-639
Gastrointestinal Bleeding in Mechanical Circulatory Support Patients
Katherine M. Klein, Vigneshwar Kasirajan
Pages 641-646
Postoperative Management Strategies in Mechanical Circulatory Support Patients
Tiffany Buda, Kimberly Miracle, Marjorie Urban
Pages 647-670
Palliative Care in MCS Patients: Insights into Current Practice and Outcomes
Krista Dobbie, Kyle Neale
Pages 671-689
Future Perspectives
Front Matter
Pages 691-691
Clinical Demands and Challenges for Future Mechanical Circulatory Support Technologies
Adam D. DeVore, Joseph G. Rogers
Pages 693-700
Smart Mechanical Circulatory Support Devices: Requirements and Perspectives
Joshua P. Cysyk, Gerson Rosenberg
Pages 701-706
Novel Solutions for Patient Monitoring and Mechanical Circulatory Support Device Control
Martin Maw, Francesco Moscato, Christoph Gross, Thomas Schlöglhofer, Heinrich Schima
Pages 707-728

This book provides a comprehensive overview of mechanical circulatory support of the failing heart in adults and children. The book uniquely combines engineering knowledge and the clinician’s perspective into a single resource, while also providing insights into current and future development of mechanical circulatory support technology, such as ventricular assist devices, the total artificial heart and catheter-based technologies for heart failure.
Topics featured in this book include:
The history of mechanical circulatory device development.
Fundamentals of hemodynamics support.
Clinical management of mechanical circulatory devices.
Surgical implantation techniques.
Current limitations of device therapies in advanced heart failure.
Advanced and novel devices in the development pipeline.
Opportunities for advancement in the field.
Mechanical Support for Heart Failure: Current Solutions and New Technologies is a must-have resource for not only physicians, residents, fellows, and medical students in cardiology and cardiac surgery, but also clinical and basic researchers in biomedical engineering with an interest in mechanical circulatory support, heart failure, and new technological applications in medicine.