Preface -- Extracellular and intracellular recordings -- Theory of electrical transfer -- Amplifier -- Salt environment -- Micropipettes -- Spatiotemporal effects of synaptic input -- Perforated patch -- Isolation of synaptic current -- Fast and slow synaptic currents -- Measuring kinetics of synaptic current -- Measuring release probability -- Long-term measurements -- Measuring reversal potentials -- Amplitude -- Pre- and post-synaptic effect -- Run-up and run-down -- Kinetics of synaptic current -- Measurements of a single synapse -- Measurements of silent synapses -- Dendritic patch -- Electrophysiological tag -- In vivo electrophysiology.

Electrophysiology is one of the finest approaches capable of detecting and analyzing electrical events in the brain. However, like all other experimental approaches, it has its limitations. This book was created to serve as a guide for those endeavoring to understand the function of electrophysiology and its underlying components: neurons, neural systems, and the brain. It introduces and highlights important topics in the field of electrophysiology, while also extending these topics to practical electrophysiological approaches through the perspective of the two authors. This book is ideal for graduate students or junior postdoctoral fellows interested in starting a journey in synaptic neuroscience.