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008			171124s2018 gw | s |||| 0|eng d
020			_a9783319631875
024	7		_a10.1007/978-3-319-63187-5 _2doi
040			_aES-MaUEC _bspa _dES-VaUE
050			_aQH599 .C47 _b2018 EB
245	1	0	_aChromatin Regulation of Early Embryonic Lineage Specification _cedited by Jason Knott, Keith Latham
264		1	_aCham _bSpringer International Publishing _bImprint: Springer _c2018
300			_a1 recurso en línea (VII, 78 páginas 16 ilustraciones a color)
336			_2rdacontent _aTexto (visual) _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	1		_aAdvances in Anatomy, Embryology and Cell Biology, _x0301-5556 ; _v229
490	0		_aMedicine (Springer-11650)
505	0		_aCHD1 controls cell lineage specification through zygotic genome activation -- Chromatin remodelling proteins and cell fate decisions in mammalian preimplantation development -- Transcriptional regulation and genes involved in first lineage specification during preimplantation development -- ROCK and RHO playlist for preimplantation development: Streaming to HIPPO pathway and apicobasal polarity in the first cell differentiation -- XEN and the art of stem cell maintenance - molecular mechanisms maintaining cell fate and self-renewal in extraembryonic endoderm stem (XEN) cell lines.  .
520	3		_aFive leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE). The second cell-fate choice encompasses the transformation of ICM into extraembryonic primitive endoderm (PE) and pluripotent epiblast. The processes, which occur during the period of preimplantation development, serve as the foundation for subsequent developmental events such as implantation, placentation, and gastrulation. The mechanisms that regulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.
988			_aEBSPRINGER_2018
700	1		_aKnott, Jason. _eeditor literario _0http://id.loc.gov/authorities/names/n2018182043 _0http://viaf.org/viaf/7152199176714280952
700	1		_aLatham, Keith. _eeditor literario _0http://id.loc.gov/authorities/names/n2018182044 _0http://viaf.org/viaf/7152199186514280968
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _0http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319631868
776	0	8	_iEdición impresa: _z9783319631882
830		0	_aAdvances in Anatomy, Embryology and Cell Biology, _x0301-5556 ; _v229
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-63187-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
998			_db _el _feng _ggw _h0