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020 _a9783319551135
024 7 _a10.1007/978-3-319-55113-5
_2doi
040 _bspa
_dES-VaUE
050 4 _aRD33.55
_b.I77 2018 EB
245 1 0 _aIrreversible Electroporation in Clinical Practice
_cedited by Martijn R. Meijerink, Hester J. Scheffer, Govindarajan Narayanan.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2018.
300 _aVI, 285 p. 89 illus., 72 illus. in color.
_bonline resource.
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 _aMedicine (Springer-11650)
505 0 _aIntroduction: History of image-guided tumor ablation -- History of electroporation. Preclinical Research: Multi-scale biophysical principles in clinical irreversible electroporation -- Numerical modelling for prediction and evaluation of treatment outcome -- The effect of irreversible electroporation on blood vessels, bile ducts, urinary tract, intestines and nerves. Technique, tips and tricks: Anaesthetic management during irreversible electroporation procedure -- Complications and procedures to enhance safety -- Treatment planning, needle insertion, image-guidance, endpoint Assessment -- Thermal effects of irreversible electroporation --  Clinical practice: Irreversible electroporation of liver tumors -- Irreversible electroporation of pancreatic tumors -- Irreversible electroporation for perihilar cholangiocarcinoma (Klatskin tumors) -- Irreversible electroporation of kidney tumors -- Irreversible Electroporation of Prostate Tumors -- Irreversible electroporation of tumors within the pelvic cavity -- Irreversible Electroporation of Lung Tumors --  Future prospectives: From local to systemic treatment: leveraging antitumor immunity following irreversible electroporation -- Future perspectives of IRE.
520 _aThis book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) – better known by its commercial name, NanoKnife – which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early clinical results, and future perspectives. Contraindications, treatment planning, potential complications, follow-up imaging, and other practical aspects are fully discussed, with highlighting of useful tips and tricks. Through the delivery of short but highly intense electrical pulses, IRE results in tumor cell membrane permeabilization, causing cells to go into apoptosis. The minimally invasive nature of IRE, combined with the prospect of completely eradicating tumors while preserving delicate structures in the ablation zone, makes IRE the object of worldwide clinical research. This book will be of value for practitioners and trainees in interventional and diagnostic radiology, surgery, medical oncology, HPB and gastroenterology, urology, and radiation oncology.
653 0 _aInterventional radiology.
653 0 _aSurgical oncology.
653 0 _aRadiotherapy.
653 0 _aRadiology, Medical.
700 1 _aMeijerink, Martijn R.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aScheffer, Hester J.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aNarayanan, Govindarajan.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_9106996
776 0 8 _iPrinted edition:
_z9783319551128
776 0 8 _iPrinted edition:
_z9783319551142
776 0 8 _iPrinted edition:
_z9783319855714
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-55113-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db