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020 _a9789811065804
024 7 _a10.1007/978-981-10-6580-4
_2doi
040 _aES-MaUEC
_bspa
_dES-VaUE
050 4 _aRC537
_b.U533 2018 EB
245 1 0 _aUnderstanding Depression:
_bVolume 1. Biomedical and Neurobiological Background
_cedited by Yong-Ku Kim.
264 1 _aSingapore
_bSpringer Singapore :
_bImprint: Springer
_c2018.
300 _a1 recurso en línea (XIII, 322 páginas 16 ilustraciones, 14 ilustraciones a color)
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aMedicine (Springer-11650)
505 0 _a1.Genetic and epigenetic aspects of depression -- 1-1.Highlights on pharmacogenetics and pharmacogenomics in depression -- 1-2.Imaging genetics studies on susceptibility genes for major depressive disorder: the present and the future -- 1-3.Gene-environmental interaction and role of epigenetic in depression -- 1-4.The role of microRNAs and long noncoding RNAs in depression: diagnosis and therapeutic implication -- 1-5.The role of early life stress in HPA axis and depression -- 2.Molecular-, cellular-level aspects of depression -- 2-1.Complex role of serotonin receptors in depression -- 2-2.Emerging role of glutamate receptors in pathophysiology of depression -- 2-3.New perspective on mTOR pathways: a new target of depression -- 2-4.Cellular aging in depression: the role of telomere-telomerase system -- 2-5.Differentiation and biological markers in subtype of depression -- 3.Neural circuit-level aspect of depression -- 3-1.Molecular, structural, and functional neuroimaging in depression -- 3-2.Resting-state activity in depression; a link to spatiotemporal psychopathology -- 3-3.Functional neuroimaging in depression: a tool to predict treatment outcome and response -- 3-4.Cortical-subcortical interactions in the pathophysiology of depression -- 3-5.Pathophysiology and treatment strategies for different types of depression -- 3-6.The effect of neurostimulation in depression -- 4.Multicellular system-level aspect of depression -- 4-1.Inflammation, depression and neurodegeneration: a possible cause of dementia in late life depression? -- 4-2.Gut-microbiota-brain axis and depression -- 4-3.The interactions of immune inflammation and oxidative and nitrosative stress with the kynurenine and melatonergic pathways in depression -- 4-4.Glia-neuron cross-talk in depression -- 4-5.Depression model in primate: relevance to novel drug discovery -- 5.Species-, individual-, gender-, culture-specific aspects of depression -- 5-1.Precision psychiatry: personalized clinical approach to depression -- 5-2.Gender differences in depression -- 5-3.An up-date on the epidemiology of major depressive disorder across cultures.
520 3 _aThis book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression and their relation to clinical manifestations and the development of more effective treatments. This first volume is devoted specifically to biomedical and neurobiological issues. Detailed information is presented on a wide range of topics, including genetics, molecular and cellular biology, and aspects at the neural circuit and multicellular system levels. Readers will gain a deeper appreciation of the factors and interactions underlying individual variation in responsiveness to stress and vulnerability to depression, as well as a clear understanding of potential treatment targets and causes of treatment resistance based on the latest research. A concluding section considers progress towards precision psychiatry and gender and cultural differences in depression. The companion volume is dedicated to clinical and management issues in depression. Understanding Depression will be an excellent source of information for both researchers and practitioners in the field.
650 7 _aPsiquiatría
_2embne
_9139041
650 7 _aNeurología.
_9139040
650 7 _aNeurociencias
_2embne
_9158907
700 1 _aKim, Yong-Ku.
_eeditor literario
_0http://id.loc.gov/authorities/names/n2017073847
_0http://viaf.org/viaf/118151352055352602259
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_0http://viaf.org/viaf/148105729
_9106996
776 0 8 _iEdición impresa:
_z9789811065798
776 0 8 _iEdición impresa:
_z9789811065811
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-10-6580-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db