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008			180109s2018 gw | s |||| 0|eng d
020			_a9783319680828
024	7		_a10.1007/978-3-319-68082-8 _2doi
040			_aES-MaUEC _bspa _dES-VaUE
050		4	_aRC644 _b.P74 2018 EB
245	1	0	_aPrecision Molecular Pathology of Liver Cancer _cedited by Chen Liu.
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2018.
300			_a1 recurso en línea (XI, 271 páginas 30 ilustraciones, 22 ilustraciones a color)
336			_2rdacontent _aTexto (visual) _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMolecular Pathology Library _x1935-987X
490	0		_aMedicine (Springer-11650)
505	0		_aOverview: Current diagnosis and treatment of HCC in the era of precision medicine -- The etiology and pathogenesis of hepatocellular carcinoma -- Histological classification of HCC and its clinical implication -- Molecular classification of HCC and precision medicine -- Recent advances in HCC genomics, next generation sequencing, and bioinformatics -- Epigenetic regulations in the pathogenesis of HCC and the clinical application -- Biomarker discovery and validation in HCC diagnosis, prognosis, and therapy -- HCC cancer stem cell signaling pathway -- Epithelial and mesenchymal transition (EMT) and its biological significance in HCC -- HCC metastasis and circulating tumor cells -- Biological role and potential clinical application of miRNA in hepatocellular carcinoma -- Immune regulation in HCC and the prospect of immunotherapy -- Liver cell dysplasia and the development of HCC -- Molecular pathogenesis of hepatic adenoma and its malignant transformation -- The role of liver biopsy in HCC early diagnosis and treatment decision -- The future prospect on surgical approaches for HCC -- The future prospect on targeted therapy for HCC. .
520	3		_aThis volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.
650		7	_9141308 _aGastroenterología
650		7	_aPatología _2embne _9138489
650		7	_aOncología _9139207
700	1		_aLiu, Chen. _eeditor literario _0http://id.loc.gov/authorities/names/no2007126749 _0http://viaf.org/viaf/166895868
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _0http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319680804
776	0	8	_iEdición impresa: _z9783319680811
776	0	8	_iEdición impresa: _z9783319885438
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-68082-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
998			_db