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020 _a9783319724225
024 7 _a10.1007/978-3-319-72422-5
_2doi
040 _bspa
_dES-MaUEC
050 _aRM302 .D78
_b2018 EB
090 4 _aRS380
090 4 _aRS190-210
245 0 0 _aDrug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions
_cedited by Manjunath P. Pai, Jennifer J. Kiser, Paul O. Gubbins, Keith A. Rodvold.
250 _a4th ed. 2018.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Humana Press
_c2018.
300 _a1 recurso en línea ( XVI, 326 páginas 8 ilustraciones, 5 ilustraciones a color)
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 1 _aInfectious Disease
490 _aMedicine (Springer-11650)
505 0 _aIntroduction to Drug-Drug Interactions -- Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion -- Mechanisms of Drug Interactions II: Transport Proteins -- Drug-Food Interactions -- Drug-Cytokine Interactions -- Interactions between Herbs and Antiinfective Medications -- In vitro Modeling of Drug-Drug Interactions -- Probe Cocktail Studies -- Design and Data Analysis in Drug Interaction Studies.
520 _aThe 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.
988 _aEBSPRINGER_MEDICINA_FEB2019
650 7 _2embne
_9169576
_aMedicamentos
_xInteracción
650 7 _2embne
_aEnfermedades infecciosas
_9138404
700 1 _aPai, Manjunath P
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aKiser, Jennifer J
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aGubbins, Paul O
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRodvold, Keith A
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_9106996
776 0 8 _iPrinted edition:
_z9783319724218
776 0 8 _iPrinted edition:
_z9783319724232
776 0 8 _iPrinted edition:
_z9783030101985
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-72422-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_feng
_ggw
_h0
_zSI