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_c10849 _d10849 |
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| 001 | 10849 | ||
| 003 | DE-He213 | ||
| 005 | 20210622040354.0 | ||
| 006 | a||||fo|||| 00| 0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 180329s2018 gw | s |||| 0|eng d | ||
| 020 | _a9783319680385 | ||
| 024 | 7 |
_a10.1007/978-3-319-68038-5 _2doi |
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| 040 |
_aES-MaUEC _bspa _dES-VaUE |
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| 050 | 4 |
_aQR186.7 _b.A58 2018 EB |
|
| 245 | 1 | 0 |
_aAntibody Therapy: _bSubstitution - Immunomodulation - Monoclonal Immunotherapy _cedited by Paul Imbach. |
| 264 | 1 |
_aCham, Switzerland _bSpringer _c2018 |
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| 300 | _a1 recurso en línea (XIV, 363 páginas 47 ilustraciones, 32 ilustraciones a color) | ||
| 336 |
_2rdacontent _aTexto (visual) _btxt |
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| 337 |
_2rdamedia _aelectrónico _bc |
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| 338 |
_2rdacarrier _arecurso electrónico _bcr |
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| 347 |
_atext file _bPDF |
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| 490 | 0 | _aMedicine (Springer-11650) | |
| 520 | 3 | _aThis practical manual, written by well-known experts, reviews current indications for the use of IgG concentrates and some other modern immunomodulators and provides fundamental information on present-day immunomodulation in patients (and mice). The book opens by tracing the transition from IgG substitution to IgG immunomodulation and providing expert updates on immunomodulatory indications in autoimmune and inflammatory disorders, including hematologic, neurologic, dermatologic, and other diseases. Basic aspects of IgG concentrates, including methods of production, safety, currently available products, and mechanisms of action, are then discussed. An entire chapter is devoted to the different aspects of immunomodulatory IgG treatment in the bleeding disorder immune thrombocytopenia (ITP). Finally, the transition from polyclonal to monoclonal antibody (mAb) treatment is addressed in detail, covering mAb development, methods, mechanisms of action, adverse effects, and more. Particular attention is paid to the example of anti-CD20 (B-cell) antibody. | |
| 650 | 7 |
_aInmunología _9138330 |
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| 650 | 7 |
_9140122 _aHematología |
|
| 650 | 7 |
_aOncología _9139207 |
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| 700 | 1 |
_aImbach, Paul. _eeditor literario _0http://id.loc.gov/authorities/names/n85349494 _0http://viaf.org/viaf/62174505 _988570 |
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| 710 | 2 |
_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _0http://viaf.org/viaf/148105729 _9106996 |
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| 776 | 0 | 8 |
_iEdición impresa: _z9783319680378 |
| 776 | 0 | 8 |
_iEdición impresa: _z9783319680392 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-68038-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia) |
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_2lcc _cLE |
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| 998 | _db | ||