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020			_a9783319719672
024	7		_a10.1007/978-3-319-71967-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
041	0		_aeng
050		4	_aRG133.5 _b.R43 2018 EB
245	0	0	_aRecurrent Implantation Failure : _bEtiologies and Clinical Management _cedited by Jason M. Franasiak, Richard T. Scott Jr
264		1	_aCham, Switzerland _bSpringer _c2018
300			_a1 recurso en línea (XIII, 215 páginas) _b32 ilustraciones, 29 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aSignaling Between Embryo and Endometrium: Normal Implantation -- Embryo and Endometrial Synchrony in Implantation Failure -- Spermatogenesis: Fertile Ground for Contributing to Recurrent Implantation Failure?- Embryonic Factors Associated with Recurrent Implantation Failure -- The Genetics of Pregnancy Failure -- Immune Factors in Recurrent Implantation Failure -- Stress and Recurrent Implantation Failure -- Hematologic Disease in Recurrent Implantation Failure -- Endocrine Causes of Recurrent Implantation Failure -- Anatomic Abnormalities and Recurrent Implantation Failure -- Microbiome in Embryonic Implantation and Recurrent Implantation Failure -- Psychosocial Implications of Recurrent Implantation Failure.
520	3		_aThis unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population. Beginning with a presentation of the mechanism of normal implantation, the physiologic synchrony between embryo and endometrium, and the roles of both gametes and embryos in RIF, the book then examines the various genetic, immune and environmental factors involved. Abnormalities of the hematologic and endocrine system, as well as those of the anatomy and microbiome, are described in detail. Last but no less important, the psychological stress and treatment of patients experiencing RIF is discussed.  Assisted reproductive technology (ART) success has increased substantially over the past three decades. However, despite these advances, recurrent implantation failure is still a common issue confronting patients and clinicians, and RIF represents one of the greatest challenges in ART and remains a source of frustration and disappointment for patients, clinicians, and researchers involved in the process. Providing an in-depth investigation into the pathophysiology and biological mechanisms of RIF and its clinical management, this will be an excellent resource for reproductive endocrinologists and infertility specialists. .
988			_aEBSPRINGER_2018
650		7	_2embne _9153562 _aReproducción humana asistida
700	1		_aFranasiak, Jason M. _eeditor literario _0http://id.loc.gov/authorities/names/n2018187627 _0http://viaf.org/viaf/4784149719138711130007
700	1		_aScott Jr., Richard T. _eeditor literario
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _0http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319719665
776	0	8	_iEdición impresa: _z9783319719689
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-71967-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942			_2lcc _cLE _n0
998			_db _zSI