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020 _a9789811079412
024 7 _a10.1007/978-981-10-7941-2
_2doi
040 _bspa
_dES-MaUEC
050 _aQP261
_b.C45 2018 EB
090 4 _aRG1-991
245 0 0 _aCell Biology of the Ovary :
_bStem Cells, Development, Cancer, and Clinical Aspects
_cedited by Hidetaka Katabuchi, Takashi Ohba, Takeshi Motohara.
264 1 _aSingapore
_bSpringer Singapore :
_bImprint: Springer
_c2018.
300 _a1 recurso en línea ( VIII, 166 páginas 32 ilustraciones, 24 ilustraciones a color)
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 _aMedicine (Springer-11650)
505 0 _aPart I. Development of ovary; 1. Reconstitution of human germ cell development in vitro -- 2. Regulation of steroidogenesis in gonads by Ad4BP/SF-1.-  3. Role of Hedgehog-BMP4 signaling in gonadogenesis -- Part II. Ovarian stem cells and cancer stem cells; 4. Role of Lgr5-expressing stem cells in epithelial renewal and cancer in reproductive tract -- 5. Characteristics of ovarian cancer stem cells.-  6. Role of CD44 variant 6 in ovarian cancer stem cells -- Part III. Strategies for fertility preservation; 7. Rescue from primary ovarian insufficiency -- 8. Ovarian tissue cryopreservation and transplantation.-  9. Clinical management of primary ovarian insufficiency -- Part IV. Molecular and clinical aspects of epithelial ovarian cancer; 10. Molecular pathogenesis of epithelial ovarian cancer.-  11. Clinical management of epithelial ovarian cancer -- 12. Molecular targeted therapy for epithelial ovarian cancer.
520 _aThis unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical aspects. Expert authors reveal the most recent findings on ovariogenesis and ovarian carcinogenesis by shedding light on stem cell biology for the ovarian surface epithelial cells or primordial germ cells. Readers will greatly increase their understanding of the relevance of the cells that constitute the ovary, which is of vast significance in comprehending the occurrence mechanism of ovarian tissue and ovarian cancer. In this way the book covers a wide range of fields concerned with the ovary. This work benefits not only gynecologists and obstetricians, but also basic researchers in the field of stem cell biology and all clinicians who are involved in the management of fertility preservation or ovarian cancer. 
988 _aEBSPRINGER_MEDICINA_FEB2019
650 7 _2embne
_9669850
_aOvarios
650 7 _2embne
_9669851
_aOvulación
700 1 _aKatabuchi, Hidetaka
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/n2018183334
700 1 _aOhba, Takashi
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/n2018188373
700 1 _aMotohara, Takeshi
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/n2018188374
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_9106996
776 0 8 _iPrinted edition:
_z9789811079405
776 0 8 _iPrinted edition:
_z9789811079429
776 0 8 _iPrinted edition:
_z9789811340239
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-10-7941-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
998 _db
_feng
_ggw
_h0
_zSI