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020			_a9781592590865
024	7		_a10.1385/1592590861 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-VaUE
050			_aRC271.G45 _b2008 EB
245	1	0	_aGene Therapy of Cancer _bMethods and Protocols _cedited by Wolfgang Walther, Ulrike Stein
250			_a1st edition 2000
264		1	_aTotowa, NJ _bHumana Press _c2000
300			_a1 recurso en línea (XVI, 645 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Medicine _x1940-6037 _v35
505	0		_aExperimental Approaces To Cancer Gene Therapy -- Immunizing Potential of Cytokine-Transduced Tumor Cells -- Particle-Mediated Gene Transfer into Dendritic Cells -- Cancer Gene Therapy With Heat Shock Protein-65 Gene -- Recombinant Vaccinia Virus MVA for Generation and Analysis of T Cell Responses Against Tumor Associated Antigens -- Experimental Approaces To Cancer Gene Therapy -- Selection of Cytochrome P450 Genes for Use in Prodrug Activation-Based Cancer Gene Therapy -- Construction of P450-Expressing Tumor Cell Lines Using Retroviruses -- 7 In Vitro Methods for Evaluation of P450-Based Anticancer Gene Therapy -- 8 Tumor Models for Evaluation of P450 Gene Therapy In Vivo -- Experimental Approaces To Cancer Gene Therapy -- 9 Intracellular Single-Chain Antibodies for Gene Therapy -- Combined Adenoviral Transfer of Tumor Suppressor and Cell-Cycle Genes for Tumor-Cell Apoptosis -- Experimental Approaces To Cancer Gene Therapy -- Inhibition of Cell Growth by Antisense Oligonucleotides Targeting the Growth-Related Protein Kinase c-raf -- IGF-1 Antisense Strategies for Cancer Treatment -- Experimental Approaces To Cancer Gene Therapy -- Anti-MDR1 Ribozyme Gene Therapy -- Anti-c-erb1B2 Ribozyme for Gene Therapy of Breast Cancer -- Anti-K-ras1 Ribozyme Adenoviral Vector for Gene Therapy of Non-Small Cell Lung Cancer -- Experimental Approaces To Cancer Gene Therapy -- Green Fluorescent Protein Retroviral Vector -- HSV-1 Vectors for Gene Therapy of Experimental CNS Tumors -- Intratumoral Injection of Naked DNA -- Cationic Liposome Gene Transfer -- In Vivo Particle-Mediated Gene Transfer for Cancer Therapy -- Gene Targeting to Hepatomas (AFP) -- Adenovirus-Mediated Targeted Gene Therapy for Breast Cancer and for Purging Hematopoietic Stem-Cell Sources -- Chemotherapy-Inducible Vector for Gene Therapy of Cancer -- Experimental Approaces To Cancer Gene Therapy -- Oncolytic Adenoviral Vectors -- Genetically Modified Clostridium for Gene Therapy of Tumors -- Tumor-Targeted Salmonella: Strain Development and Expression of the HSV-tK Effector Gene -- Clinical Protocols for Cancer Gene Therapy -- Ex Vivo Cytokine Gene Transfer in Melanomas by Using Particle Bombardment -- Intratumoral Gene Transfer of the HLA-B7 Gene Into Colon Carcinoma Metastases -- Hybrid Cell Vaccination in Patients With Metastatic Melanoma -- Clinical Protocols for Cancer Gene Therapy -- Retroviral Transfer of the Herpes Simplex Virus-Thymidine Kinase (HSV-tK) Gene for the Treatment of Cancer -- Gene Therapy for Treatment of Brain Tumors (HSV-tKIn Vivo Gene Transfer) -- Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK -- Intratumoral Gene Transfer of the Cytosine Deaminase Gene for the Treatment of Breast Cancer -- Clinical Protocols for Cancer Gene Therapy -- Adenovirus-Mediated Wild-Type p53 Gene Transfer into Head and Neck Cancers -- Direct DNA Injection (p53) into HCC Tumors -- A Phase II Trial of Intratumoral Injection with a Selectively Replicating Adenovirus (ONYX-015) in Patients with Recurrent, Refractory Squamous Cell Carcinoma of the Head and Neck -- Clinical Protocols for Cancer Gene Therapy -- c-myb Antisense Oligonucleotide Therapeutics for Hematologic Malignancies -- Ovarian Cancer Gene Therapy with BRCA1-An Overview -- Methods for Chemoprotection and Chemosensitization.
520			_aIn Gene Therapy of Cancer: Methods and Protocols, Wolfgang Walther and Ulrike Stein survey the rapidly evolving field cancer gene therapy and provide a broad array of leading-edge protocols for the delivery of therapeutic genes into tumors. Described in step-by-step fashion and enriched with each author's own practical tips, these readily reproducible methods are currently being widely applied in cancer gene therapy investigations, including immunotherapy and tumor vaccination, suicide gene therapy, antioncogene therapy, and antisense and ribozyme gene therapy. Representative strategies are provided for gene targeting and for viral or nonviral gene delivery in cancer therapy, as well as a significant number of clinical protocols for the development of novel cancer gene therapies. Gene Therapy of Cancer: Methods and Protocols offers basic and clinical researchers a broad ranging overview and collection of the most recent advances in gene transfer techniques. Written by leading international authorities, its readily reproducible, cutting-edge methods constitute today's most valuable tools for the study of cancer gene therapy in both the laboratory and clinical trials.
988			_aSpringer_Protocols_2000
650		7	_2embne _9273311 _aMedicina
650		0	_9516571 _aOncología
700	1		_aWalther, Wolfgang _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aStein, Ulrike _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9780896037144
776	0	8	_iPrinted edition: _z9781489941831
776	0	8	_iPrinted edition: _z9780896038431
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592590861 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
998			_db