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020 _a9781071610121
024 7 _a10.1007/978-1-0716-1012-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aViruses as Therapeutics
_bMethods and Protocols
_cedited by Alexandra R. Lucas.
250 _a1st edition 2021
264 1 _aNew York, NY
_bSpringer International Publising
_c2021
300 _a1 recurso en línea (XIV, 294 páginas)
_b59 ilustraciones, 52 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2225
505 0 _aViruses for Landscape-Scale Therapy: Biological Control of Rabbits in Australia -- Development and Expression of Subunit Vaccines against Viruses in Plants -- Development of Antiviral Vaccine Utilizing Self-Destructing Salmonella for Antigen and DNA Vaccine Delivery -- Methods for the Construction of Recombinant Oncolytic Myxoma Viruses -- Molecular Design and Production of AAV Viral Vectors for Gene Therapy -- Murine Model of Thermal Burn Injury for Evaluating Protein Therapeutics Derived from Viruses -- Deriving Immune Modulating Peptides from Viral Serine Protease Inhibitors (Serpins) -- Methods for Crystallization and Structural Determination of M-T7 Protein from Myxoma Virus -- Microscopic Analysis of Viral Infection -- Metabolomics Analysis of Viral Therapeutics -- Detecting Necroptosis in Virus-Infected Cells -- Topical Application of Virus‐Derived Immunomodulating Proteins and Peptides to Promote Wound Healing in Mouse Models -- Neurologic and Histologic Tests Used to Measure Neuroprotective Effectiveness of Virus-Derived Immune Modulating Proteins -- Pre-Clinical Testing of Viral Therapeutic Efficacy in Pristane-Induced Lupus Nephritis and Diffuse Alveolar Hemorrhage Mouse Models -- Kidney Subcapsular Allograft Transplants as a Model to Test Virus-Derived Chemokine Modulating Proteins as Therapeutics -- A Mouse Model of Acute Liver Injury by Warm, Partial Ischemia-Reperfusion for Testing the Efficacy of Virus-Derived Therapeutics.
520 _aThis detailed volume explores methods and techniques reflecting how viruses can be a beneficial force for all levels of life as well as the mammalian microbiota. Beginning with methods for the development and study of viruses, the book continues with current techniques and approaches used to develop new treatments from virus-derived vaccines to vectors and proteins, such as a range of models and methods designed to measure therapeutic efficacy of virus-derived biologics and therapeutic proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Viruses as Therapeutics: Methods and Protocols is an ideal guide for researchers working to further understand how viruses can benefit lifeforms and even prevent damage from other viruses.
700 1 _aLucas, Alexandra R
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781071610114
776 0 8 _iPrinted edition:
_z9781071610138
776 0 8 _iPrinted edition:
_z9781071610145
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1012-1
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2021
999 _c233027
_d233027