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020 _a9781071615348
024 7 _a10.1007/978-1-0716-1534-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aModeling Transcriptional Regulation
_bMethods and Protocols
_cedited by SHAHID MUKHTAR.
250 _a1st edition 2021
264 1 _aNew York, NY
_bSpringer International Publising
_c2021
300 _a1 recurso en línea (XI, 307 páginas)
_b104 ilustraciones, 59 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2328
505 0 _aCo-expression Networks in Predicting Transcriptional Gene Regulation -- Inference of Gene Coexpression Networks from Bulk-based RNA-Sequencing Data -- Genomic Footprinting Analyses from DNase-seq data to Construct Gene Regulatory Networks -- Spatiotemporal Gene Expression Profiling and Network Inference: A Roadmap For Analysis, Visualization, and Key Gene Identification -- Dynamic Modeling of Transcriptional Gene Regulatory Networks- Mathematical Programming for Modelling Expression of a Gene using Gurobi Optimizer to Identify its Transcriptional Regulators -- Multiscale Modeling of Cross-Regulatory Transcript and Protein Influences -- Biological Network Mining -- Identification of Gene Regulatory Networks from Single-Cell Expression Data- Inference of Gene Regulatory Network From Single-Cell Transcriptomic Data using pySCENIC -- Modeling Immune Dynamics in Plants using JIMENA-package -- Dynamic Regulatory Event Mining by iDREM in Large Scale Multi-Omics Datasets during Biotic and Abiotic Stress in Plants -- A semi-in vivo Transcriptional Assay to Dissect Plant Defense Regulatory Modules -- Assessing Global Circadian Rhythm through Single-Time-Point Transcriptomic Analysis -- High-throughput Targeted Transcriptional Profiling of Defense Genes using RNA-mediated oligonucleotide Annealing, Selection, and Ligation with next-generation sequencing in Arabidopsi -- Rapid Validation of Transcriptional Enhancers Using a Transient Reporter Assay -- Computational Identification of ceRNA and Reconstruction of ceRNA Regulatory Network Based on RNA-seq and Small RNA-seq Data in Plants -- In Silico Prediction for ncRNAs in Prokaryotes -- Mathematical Linear Programming to Model MicroRNAs-Mediated Gene Regulation Using Gurobi Optimizer. .
520 _aThis book provides methods and techniques used in construction of global transcriptional regulatory networks in diverse systems, various layers of gene regulation and mathematical as well as computational modeling of transcriptional gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Modeling Transcriptional Regulation: Methods and Protocols aims to provide an in depth understanding of new techniques in transcriptional gene regulation for specialized audience.
700 1 _aMUKHTAR, SHAHID
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781071615331
776 0 8 _iPrinted edition:
_z9781071615355
776 0 8 _iPrinted edition:
_z9781071615362
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1534-8
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2021
999 _c233030
_d233030