000			03717nam a22003735i 4500
001			233070
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007			cr nn 008mamaa
008			180726s2018 xxu| s |||| 0|eng d
020			_a9781493986613
024	7		_a10.1007/978-1-4939-8661-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aTargeted Drug Delivery _bMethods and Protocols _cedited by Rachael W. Sirianni, Bahareh Behkam.
250			_a1st edition 2018
264		1	_aNew York, NY _bSpringer International Publising _c2018
300			_a1 recurso en línea (XI, 230 páginas) _b52 ilustraciones, 39 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1831
505	0		_aSynthesis of Cationic Polymer Libraries for Gene Delivery using Diglycidyl Ethers -- Generation of Ultra-Small PLGA Nanoparticles by Sequential Centrifugation -- Construction of Bacteria-Based Cargo Carriers for Targeted Cancer Therapy -- Production of Extracellular Vesicles Loaded with Therapeutic Cargo -- Delivery of Cytotoxic Mesenchymal Stem Cells with Biodegradable Scaffolds for Treatment of Postoperative Brain Cancer -- Nanoparticles for Targeted Drug Delivery to Cancer Stem-Like Cells and Tumor -- Exploiting Phage Display for Development of Novel Cellular Targeting Strategies -- CD44 Targeted Lipid Nanoparticles for MicroRNA Therapy -- Ultrasound and Microbubble-Mediated Blood-Brain Barrier Disruption for Targeted Delivery of Therapeutics to the Brain -- In Vitro Validation of Targeting and Comparison to Mathematical Modeling -- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles -- Tunable Collagen Microfluidic Platform to Study Nanoparticle Transport in the Tumor Microenvironment -- Utilizing the Lung as a Model to Study Nanoparticle Based Drug Delivery Systems -- Non-Enzymatic Tissue Homogenization for Biodistribution Analysis -- Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents.
520			_aThis volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.
700	1		_aSirianni, Rachael W _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aBehkam, Bahareh _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493986590
776	0	8	_iPrinted edition: _z9781493986606
776	0	8	_iPrinted edition: _z9781493993574
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-8661-3 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c233070 _d233070