000			03454nam a22003735i 4500
001			233075
003			ES-VaUE
005			20221220020436.0
007			cr nn 008mamaa
008			180820s2018 xxu| s |||| 0|eng d
020			_a9781493977505
024	7		_a10.1007/978-1-4939-7750-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aMitophagy _bMethods and Protocols _cedited by Nobutaka Hattori, Shinji Saiki.
250			_a1st edition 2018
264		1	_aNew York, NY _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XI, 180 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1759
505	0		_aShort Overview of PINK1/Parkin-mediated Mitophagy -- Induction of PINK1/Parkin-Mediated Mitophagy -- Immunocytochemical Monitoring of PINK1/Parkin-mediated Mitophagy in Cultured Cells -- The Use Of Correlative Light-electron Microscopy (CLEM) To Study PINK1/Parkin-mediated Mitophagy -- Observation Of Parkin-mediated Mitophagy in Pancreatic Beta-cells -- Monitoring Mitochondrial Changes by Alteration of the PINK1-Parkin Signaling in Drosophila -- Assessment of Mitophagy in iPS Cell-derived Neurons -- Investigation of Yeast Mitophagy with Fluorescence Microscopy and Western Blotting -- Mitopho8∆60 Assay as a Tool to Quantitatively Measure Mitophagy Activity -- Mitophagy in Yeast: A Screen of Mitophagy-Deficient Mutants -- Flow Cytometer Monitoring of Bnip3 and Bnip3L/Nix-dependent Mitophagy -- Exploring Micrornas on Nix-Dependent Mitophagy -- Monitoring of Atg5-Independent Mitophagy -- Monitoring of Paternal Mitochondrial Degradation In Caenorhabditis Elegans -- Detection of Hypoxia-induced and Iron Depletion-induced Mitophagy in Mammalian Cells -- Monitoring Mitophagy during Ageing in Caenorhabditis Elegans -- Iron-Starvation Induced Mitophagy in Yeast.
520			_aThis volume focuses on mitophagy providing methods and protocols on the methodologies and the background information on monitoring mitophagy. Chapters detail the analysis of mitophagy in connection with Parkinson's disease, especially young onset Parkinson's disease impaired by PINK/parkin pathway, Drosophila, yeast, and Caenorhabditis elegans models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mitophagy: Methods and Protocols aims to stimulate and encourage researchers to carry out ongoing and new investigations into mitophagy.
700	1		_aHattori, Nobutaka _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSaiki, Shinji _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493977499
776	0	8	_iPrinted edition: _z9781493977512
776	0	8	_iPrinted edition: _z9781493992744
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7750-5 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c233075 _d233075