000			04168nam a22003855i 4500
001			233090
003			ES-VaUE
005			20221220020437.0
007			cr nn 008mamaa
008			191226s2020 xxu| s |||| 0|eng d
020			_a9781071602270
024	7		_a10.1007/978-1-0716-0227-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aPeptide Synthesis _bMethods and Protocols _cedited by Waleed M. Hussein, Mariusz Skwarczynski, Istvan Toth.
250			_a1st edition 2020
264		1	_aNew York, NY _bSpringer International Publising _c2020
300			_a1 recurso en línea (XI, 338 páginas) _b135 ilustraciones, 56 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2103
505	0		_aSolution Phase Peptide Synthesis: The Case of Biphalin -- Application of Fmoc-SPPS, Thiol-Maleimide Conjugation and Copper(I)-Catalyzed Alkyne-Azide Cycloaddition "Click" Reaction in the Synthesis of a Complex Peptide-Based Vaccine Candidate against Group A Streptococcus -- In Situ Neutralization Protocols for Boc-SPPS -- Anhydrous Hydrogen Fluoride Cleavage in Boc Solid Phase Peptide Synthesis -- Automated Solid-Phase Peptide Synthesis -- New Developments in Microwave-Assisted Solid Phase Peptide Synthesis -- Protecting Groups in Peptide Synthesis -- Synthesis of O-Acyl Isopeptides: Stepwise and Convergent Solid-Phase Synthesis -- An Isodipeptide Building Block for Microwave-Assisted Solid-Phase Synthesis of Difficult Sequence-Containing Peptides -- SPOT Synthesis: The Solid-Phase Peptide Synthesis on Planar Surfaces -- Solid-Phase Synthesis of Wollamide Cyclohexapeptide Analogs -- Synthesis of Branched Peptides via a Side-Chain Benzyl Ester -- Solid Phase Synthesis of Octapeptin Lipopeptides -- Peptidomimetic Synthesis-Drug Discovery for Alzheimer's Disease -- Synthesis of Amide Backbone-Modified Peptides -- Synthesis of NickFects, a New Family of CPPs, by Solid-Phase Peptide Synthesis -- Chemoenzymatic Synthesis of HIV-1 Glycopeptide Antigens -- Synthesis of Antimicrobial Lipopeptides Using the "CLipPA" Thiol-Ene Reaction -- Decarboxylative Couplings for Late-Stage Peptide Modifications -- Peptide and Pseudopeptide Bond Synthesis in Phosphorus Dipeptide Analogs -- Micro-Bioreactor Techniques for the Production and Spectroscopic Characterization of Microbial Peptides -- Metal Peptide Complexes for Study Neurodegenerative Diseases.
520			_aThis book provides a variety of procedures for synthetically producing peptides and their derivatives, ensuring the kind of precision that is of paramount importance for successful synthesis. Numerous techniques relevant to drugs and vaccines are explored, such as conjugation and condensation methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Synthesis: Methods and Protocols serves as an essential guide to the many crucial processes that will allow researchers to efficiently prepare, purify, characterize, and use peptides for chemical, biochemical, and biological studies.
700	1		_aHussein, Waleed M _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSkwarczynski, Mariusz _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aToth, Istvan _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781071602263
776	0	8	_iPrinted edition: _z9781071602287
776	0	8	_iPrinted edition: _z9781071602294
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0227-0 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2020
999			_c233090 _d233090