000			03934nam a22003615i 4500
001			233102
003			ES-VaUE
005			20221220020438.0
007			cr nn 008mamaa
008			200514s2020 xxu| s |||| 0|eng d
020			_a9781071605929
024	7		_a10.1007/978-1-0716-0592-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aAging _bMethods and Protocols _cedited by Sean P. Curran.
250			_a1st edition 2020
264		1	_aNew York, NY _bSpringer International Publising _c2020
300			_a1 recurso en línea (XII, 277 páginas) _b48 ilustraciones, 37 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2144
505	0		_aMeasuring the Replicative Lifespan of Saccharomyces cerevisiae using the HYAA Microfluidic Platform -- Analysis of Lifespan in C. elegans: Low- and High-Throughput Approaches -- Simple Culture Apparatus for Individual C. elegans Culture -- Analysis of Drosophila melanogaster Life Span -- Assessment of Mouse Fitness as Determined through Treadmill Running and Walking -- Human Population Genetics in Aging Studies for Molecular Biologists -- Design and Analysis of Pharmacological Studies in Aging -- Methods for Assessing Fertility in C. elegans from a Single Population -- Metabolic Assessment of Lipid Abundance and Distribution -- Quantitative Profiling of Lipid Species in Caenorhabditis elegans with Gas Chromatography-Mass Spectrometry -- Assessing Insulin and Glucose Tolerance in the Aging Mouse -- High-throughput Assessment of Changes in the Caenorhabditis elegans Gut Microbiome -- Measurements of Innate Immune Function in C. elegans -- Measuring Phagocytosis in Bone Marrow-Derived Macrophages and Peritoneal Macrophages with Aging -- Chromatin Immunoprecipitation from Caenorhabditis elegans Somatic Cells -- Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age -- Measuring Tissue-specific Autophagy Flux in Adult Caenorhabditis elegans -- Assay Development and Measurement of the Aging Biomarker Humanin -- Staining and Quantification of β-amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease -- Multimodal Imaging of Cerebral Microhemorrhages and White Matter Degradation in Geriatric Patients with Mild Traumatic Brain Injury -- Detection of HNE Modification of Proteins in Aging Mouse Tissues: A Western Blot-based Approach -- Measurements of Hydrogen Peroxide and Oxidative DNA Damage in a Cell Model of Premature Aging. .
520			_aThis volume details the impact of aging on biological system and to understand the basis of this diversity with the goal of elucidating mechanisms to optimize health. Chapters guide readers through different animal models and methodologies to examine aging at the organism, tissue, cellular, and molecular levels across the lifespan. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Aging: Methods and Protocols aims to ensure successful results in the further study of this vital field.
700	1		_aCurran, Sean P _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781071605912
776	0	8	_iPrinted edition: _z9781071605936
776	0	8	_iPrinted edition: _z9781071605943
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0592-9 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2020
999			_c233102 _d233102