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020 _a9781071609477
024 7 _a10.1007/978-1-0716-0947-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aEpistasis
_bMethods and Protocols
_cedited by Ka-Chun Wong.
250 _a1st edition 2021
264 1 _aNew York, NY
_bSpringer International Publising
_c2021
300 _a1 recurso en línea (X, 402 páginas)
_b167 ilustraciones, 85 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2212
505 0 _aMass-based Protein Phylogenetic Approach to Identify Epistasis -- SNPInt-GPU: Tool for epistasis testing with multiple methods and GPU acceleration -- Epistasis-based Feature Selection Algorithm -- W-test for Genetic Epistasis Testing -- The Combined Analysis of Pleiotropy and Epistasis (CAPE) -- Two-Stage Testing for Epistasis: Screening and Veri_cation -- Using Collaborative Mixed Models to Account for Imputation Uncertainty in Transcriptome-Wide Association Studies -- Phenotype Prediction under Epistasis -- Simulating Evolution in Asexual Populations with Epistasis -- Protocol for Construction of Genome-Wide Epistatic SNP Networks using WISH-R Package -- Brief survey on Machine Learning in Epistasis -- First-Order Correction of Statistical Significance for Screening Two-Way Epistatic Interactions -- Gene-Environment Interaction: AVariable Selection Perspective -- Using C-JAMP to Investigate Epistasis and Pleiotropy -- Identifying the Significant Change of Gene Expression in Genomic Series Data -- Analyzing High-Order Epistasis from Genotype-phenotype Maps Using 'Epistasis' Package -- Deep Neural Networks for Epistatic Sequences Analysis -- Protocol for Epistasis Detection with Machine Learning Using GenEpi Package -- A Belief Degree Associated Fuzzy Multifactor Dimensionality Reduction Framework for Epistasis Detection -- Epistasis Detection Based on Epi-GTBN -- Epistasis Analysis: Classification through Machine Learning Methods -- Genetic Interaction Network Interpretation: A Tidy Data Science Perspective -- Trigenic Synthetic Genetic Array (τ-SGA) Technique for Complex Interaction Analysis.
520 _aThis volume explores methods and protocols for detecting epistasis from genetic data. Chapters provide methods and protocols demonstrating approaches to identify epistasis, genetic epistasis testing, genome-wide epistatic SNP networks, epistasis detection through machine learning, and complex interaction analysis using trigenic synthetic genetic array (τ-SGA). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Epistasis: Methods and Protocols aims to ensure successful results in the further study of this vital field. .
700 1 _aWong, Ka-Chun
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781071609460
776 0 8 _iPrinted edition:
_z9781071609484
776 0 8 _iPrinted edition:
_z9781071609491
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0947-7
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2021
999 _c233235
_d233235