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001			233272
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008			191127s2020 xxu| s |||| 0|eng d
020			_a9781071602034
024	7		_a10.1007/978-1-0716-0203-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aCell Reprogramming for Immunotherapy _bMethods and Protocols _cedited by Samuel G. Katz, Peter M. Rabinovich.
250			_a1st edition 2020
264		1	_aNew York, NY _bSpringer International Publising _c2020
300			_a1 recurso en línea (XII, 343 páginas) _b41 ilustraciones, 34 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2097
505	0		_aT Cell Reprogramming against Cancer -- Identification of Cell Surface Targets for CAR T Cell Immunotherapy -- Microfluidic Approach for Highly Efficient Viral Transduction -- Single-cell Cytokine Analysis to Characterize CAR-T Cell Activation -- Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells -- Engineering of Natural Killer Cells for Clinical Application -- Dextran Enhances the Lentiviral Transduction Efficiency of Murine and Human Primary NK Cells -- In vivo Assessment of NK Cell-Mediated Cytotoxicity by Adoptively Transferred Splenocyte Rejection -- Immunomodulation of NK Cell Activity -- An Overview of Advances in Cell-based Cancer Immunotherapies Based on the Multiple Immune-cancer Cell Interactions -- Rapid Production of Physiologic Dendritic Cells (phDC) for Immunotherapy -- Reprogramming Exosomes for Immunotherapy -- Nanoparticles for Immune Cell Reprogramming and Reengineering of Tumor Microenvironment -- CRISPR/Cas9 Gene Targeting in Primary Mouse Bone Marrow Derived Macrophages -- Genome-Wide CRISPRi/a Screening in an In Vitro Co-culture Assay of Human Immune Cell with Tumor Cells -- The Propagation and Quantification of Two Emerging Oncolytic Viruses: Vesicular Stomatitis (VSV) and Zika (ZIKV) -- Radiolabeling and Imaging of Adoptively Transferred Immune Cells by Positron Emission Tomography -- Functional Analysis of Human Hematopoietic Stem Cells in vivo in Humanized Mice -- Monitoring Allogeneic CAR-T Cells using Flow Cytometry -- Key Factors in Clinical Protocols for Adoptive Cell Therapy in Melanoma -- Place of Academic GMP Facilities in Modern Cell Therapy. .
520			_aThis volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Reprogramming for Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
700	1		_aKatz, Samuel G _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aRabinovich, Peter M _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781071602027
776	0	8	_iPrinted edition: _z9781071602041
776	0	8	_iPrinted edition: _z9781071602058
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0203-4 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2020
999			_c233272 _d233272