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008			200729s2021 xxu| s |||| 0|eng d
020			_a9781071607879
024	7		_a10.1007/978-1-0716-0787-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aRNA Editing _bMethods and Protocols _cedited by Ernesto Picardi, Graziano Pesole.
250			_a1st edition 2021
264		1	_aNew York, NY _bSpringer International Publising _c2021
300			_a1 recurso en línea (XV, 352 páginas) _b47 ilustraciones, 43 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2181
505	0		_aSubstitutional RNA Editing in Plant Organelles -- Computational Detection of Plant RNA Editing Events -- Discovering RNA Editing Events in Fungi -- C-to-U RNA Editing: From Computational Detection to Experimental Validation -- Live Cell Quantification of APOBEC1-mediated RNA Editing: A Comparison of RNA Editing Assays -- Adenosine to Inosine RNA Editing Enzyme ADAR and microRNAs -- Quantitative Analysis of Adenosine-to-Inosine RNA Editing -- Discovering A-to-I RNA Editing Through Chemical Methods -- ALU A-to-I RNA Editing - Millions of Sites and Many Open Questions -- RNA Editing in Human and Mouse Tissues -- Bioinformatics Resources for RNA Editing -- High-throughput Sequencing to Detect DNA-RNA Changes -- Detection of A-to-I Hyper-Edited RNA Sequences -- Proteome Diversification by RNA Editing -- MicroRNA Editing Detection and Function: A Combined in silico and Experimental Approach for the Identification and Validation of Putative Oncogenic Targets -- RNA Editing in Interferonopathies -- The Role of RNA Editing in the Immune Response -- RNA Editing in Neurological and Neurodegenerative Disorders -- New Frontiers for Site-directed RNA Editing - Harnessing Endogenous ADARs. .
520			_aThis volume provides an overview about main RNA editing mechanisms, focusing on their functions in physiological as well as pathological conditions. Chapters guide readers through state- of-the art methodologies to investigate RNA editing through wet and dry approaches.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Editing: Methods and Protocols aims to ensure successful results in the further study of this vital field. .
700	1		_aPicardi, Ernesto _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aPesole, Graziano _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781071607862
776	0	8	_iPrinted edition: _z9781071607886
776	0	8	_iPrinted edition: _z9781071607893
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0787-9 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2021
999			_c233459 _d233459