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020 _a9781071611036
024 7 _a10.1007/978-1-0716-1103-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aDeep Sequencing Data Analysis
_cedited by Noam Shomron.
250 _a2nd edition 2021
264 1 _aNew York, NY
_bSpringer International Publising
_c2021
300 _a1 recurso en línea (X, 374 páginas)
_b92 ilustraciones, 81 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2243
505 0 _aDetecting Causal Variants in Mendelian Disorders using Whole Genome Sequencing -- Statistical Considerations on NGS Data for Inferring Copy Number Variations -- Applications of Community Detection Algorithms to Large Biological Datasets -- Processing and Analysis of RNA-seq data from Public Resources -- Improved Analysis of High-throughput Sequencing Data Using Small Universal k-mer Hitting Sets -- An Introduction to Whole-metagenome Shotgun Sequencing Studies -- Microbiome Analysis using 16S Amplicon Sequencing: From Samples to ASVs -- RNA-Seq in Non-model Organisms -- Deep Learning Applied on Next Generation Sequencing Data Analysis -- Interrogating the Accessible Chromatin Landscape of Eukaryote Genomes using ATAC-seq -- Genome-Wide Noninvasive Prenatal Diagnosis of SNPs and Indels -- Genome-wide Noninvasive Prenatal Diagnosis of De Novo Mutations -- Accurate Imputation of Untyped Variants from Deep Sequencing Data -- Multi-region Sequence Analysis to Predict Intratumor Heterogeneity and Clonal Evolution -- Overcoming Interpretability in Deep Learning Cancer Classification -- Single-cell Transcriptome Profiling -- Biological Perspectives of RNA-sequencing Experimental Design -- Analysis of microRNA Regulation in Single Cells -- DNA Data Collection and Analysis in the Forensic Arena. .
520 _aThis second edition provides new and updated chapters from expert researchers in the field detailing methods used to study the multi-facet deep sequencing data field. Chapters guide readers through techniques for processing RNA-seq data, microbiome analysis, deep learning methodologies, and various approaches for the identification of sequence variants. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Deep Sequencing Data Analysis: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
700 1 _aShomron, Noam
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781071611029
776 0 8 _iPrinted edition:
_z9781071611043
776 0 8 _iPrinted edition:
_z9781071611050
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1103-6
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2021
999 _c233483
_d233483