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008			210504s2021 xxu| s |||| 0|eng d
020			_a9781071613191
024	7		_a10.1007/978-1-0716-1319-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aCerebrospinal Fluid Biomarkers _cedited by Charlotte E. Teunissen, Henrik Zetterberg.
250			_a1st edition 2021
264		1	_aNew York, NY _bSpringer International Publising _c2021
300			_a1 recurso en línea (XII, 236 páginas) _b67 ilustraciones, 34 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v168
505	0		_aCSF Cell: Cell Count, Cytomorphology, Cytology, and Immunophenotyping -- Nephelometry and Turbidimetry: Methods to Quantify Albumin and Immunoglobins Concentrations in Clinical Neurochemistry -- Oligoclonal Bands: Isoelectric Focusing and Immunoblotting, and Determination of Free Light Chains in the Cerebrospinal Fluid -- Abeta CSF LC-MS -- Immunoassay and Mass Spectrometry Methods for Tau Protein Quantification in the Cerebrospinal Fluid -- CSF RT-QuIC and the Diagnosis of Creutzfeldt-Jakob Disease -- Lumbar Puncture: Consensus Guidelines -- Pre-Analytical Processing and Biobanking Protocol for CSF Samples -- Communicating Complex Results of Cerebrospinal Fluid Analysis -- Method and Clinical Validation of Biomarkers for Neurodegenerative Diseases -- Sample Preparation for Proteomic Analysis of Cerebrospinal Fluid -- Brain Biomarkers: Follow Up of RNA Expression Discovery Approach - CSF Assays for Neurogranin, SNAP-25, and VILIP-1 -- Quantification of the Neurofilament Light Chain Protein by Single Molecule Array (Simoa) Array.
520			_aThis volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer's disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
700	1		_aTeunissen, Charlotte E _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aZetterberg, Henrik _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781071613184
776	0	8	_iPrinted edition: _z9781071613207
776	0	8	_iPrinted edition: _z9781071613214
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1319-1 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2021
999			_c233495 _d233495