000			03756nam a22003615i 4500
001			233572
003			ES-VaUE
005			20221220020508.0
007			cr nn 008mamaa
008			180503s2018 xxu| s |||| 0|eng d
020			_a9781493974450
024	7		_a10.1007/978-1-4939-7445-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aIntegrin Targeting Systems for Tumor Diagnosis and Therapy _cedited by Eleonora Patsenker.
250			_a1st edition 2018
264		1	_aNew York, NY _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XI, 226 páginas) _b68 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aTumor Targeting by RGD-Grafted PLGA-Based Nanotheranostics Loaded with Paclitaxel and Superparamagnetic Iron Oxides -- Fabrication of cRGD Conjugated Dual Responsive Micelles to Target αvβ5 Integrin Overexpressed Cancer.- Copper-Free Click Chemistry Modification of Nanovectors for Integrin Targeted Cancer Therapy.- Preparation, Characterization, and In Vitro and In Vivo Evaluation of PEGylated Liposomal Doxorubicin Modified with Different cRGD Peptides -- Preparation of Heterobivalent and Multivalent Radiopharmarmaceuticals to Target Tumors Over-Expressing Integrins.- 177Lu Labeled RGD-BBN Peptide for Targeting Prostate Cancer -- Integrin-Mediated Targeting of Liposomally-Bound siRNAs to Tumor Vasculatures -- Integrin αvβ3-Targeted Optical Imaging with Metal Oxide Nanomaterials: Focusing on Zinc Oxide -- Integrin Targeting Using RGD-Based Peptide Amphiphiles -- Cyclic-RGDfK-Directed Docetaxel Loaded Nanomicelles for Angiogenic Tumor Targeting -- Targeting Glioma Cancer Cells with Fluorescent Nanodiamonds Via Integrin Receptors.- NIR Imaging-Guided Photothermal Therapy by cRGD-Conjugated Solid Lipid Nanoparticles Encapsulating IR-780 -- Synergistic Active Targeting to B16F10 Tumors by αvβ3/CD44-Targeted Nanoparticles Loaded with Docetaxel.
520			_aThis volume collects a variety of techniques and methodologies developed to facilitate research on integrin biology and to identify ideal targets and approaches for the treatment of multiple organ diseases, with a focus on cancer in particular. The chapters consecutively describe the tools for structural analysis, identification and detection of integrins as biomarkers, and include thorough laboratory and clinically-related methods on different strategies for generation, synthesis and evaluation of probes, carriers, peptides or small particles for integrin targeting, imaging, and drug delivery. As part of the Methods in Pharmacology and Toxicology series, this book contains the practical details that are invaluable in the laboratory.  Authoritative and advantageous, Integrin Targeting Systems for Tumor Diagnosis and Therapy serves readers from a wide spectrum, including researchers and students seeking an overview of existing developments, as well as leading professionals aiming to become more familiar with integrin-related innovative technologies in cancer research.
700	1		_aPatsenker, Eleonora _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493974436
776	0	8	_iPrinted edition: _z9781493974443
776	0	8	_iPrinted edition: _z9781493992478
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7445-0 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c233572 _d233572