000			03241nam a22003615i 4500
001			233659
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007			cr nn 008mamaa
008			180521s2018 xxu| s |||| 0|eng d
020			_a9781493978458
024	7		_a10.1007/978-1-4939-7845-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aProstate Cancer _bMethods and Protocols _cedited by Zoran Culig.
250			_a1st edition 2018
264		1	_aNew York, NY _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XI, 264 páginas) _b45 ilustraciones, 40 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1786
505	0		_aGeneration of Prostate Cancer Patient-derived Xenografts to Investigate Mechanisms of Novel Treatments and Treatment Resistance -- Methods to Study Angiogenesis in a Mouse Model of Prostate Cancer -- Methodologies Applied to Establish Cell Cultures in Prostate Cancer -- Protocols for Migration and Invasion Studies in Prostate Cancer -- Transplantable Animal Studies and Whole-body Optical Imaging in Prostate Carcinoma -- Protocols for Tissue Microarrays in Prostate Cancer Studies -- Functional Studies on Steroid Receptors -- Protocols for Studies on TMPRSS/ERG in Prostate Cancer -- Protocols for the Study of Taxanes Chemosensitivity in Prostate Cancer -- A Method for Prostate and Breast Cancer Cell Spheroid Cultures using Gelatin Methacryloyl-based Hydrogels -- Protocols for Studies on Genetically Engineered Mouse Models in Prostate Cancer -- Protocols for Studies on Stromal Cells in Prostate Cancer -- Techniques for Evaluation of AR Transcriptional Output and Recruitment to DNA -- NMR-based Prostate Cancer Metabolomics -- Studies on Steroid Receptor Coactivators in Prostate Cancer.
520			_aThis volume presents methods and protocols on modern analysis of steroid receptor and prostate cancer function. Chapters detail androgen, androgen receptor action, anti-androgen enzalutamide, in vitro and in vivo models, imaging, gene fusions, and help facilitate studies with novel drugs including anti-androgens and chemotherapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Prostate Cancer: Methods and Protocols aims to provide easily reproducible techniques.
700	1		_aCulig, Zoran _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493978434
776	0	8	_iPrinted edition: _z9781493978441
776	0	8	_iPrinted edition: _z9781493993024
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7845-8 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c233659 _d233659