000			04205nam a22003495i 4500
001			233819
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007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9781597455480
024	7		_a10.1007/978-1-59745-548-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aEnvironmental Genomics _cedited by C. Cristofre Martin.
250			_a1st edition 2008
264		1	_aTotowa, NJ _bHumana Press _c2008
300			_a1 recurso en línea (XII, 364 páginas) _b63 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v410
505	0		_aGene Expression Profiling -- High Throughput Whole Mount In Situ Hybridization of Zebrafish Embryos for Analysis of Tissue-Specific Gene Expression Changes After Environmental Perturbation -- Fluorescent RNA Arbitrarily Primed Polymerase Chain Reaction -- Isolation of O$3$-Response Genes from Arabidopsis thaliana Using cDNA Macroarray -- Use of cDNA Macroarrays and Gene Profiling for Detection of Effects of Environmental Toxicants -- Constructing and Screening a cDNA Library -- Comparative Molecular Physiological Genomics -- Proteomic Analysis of Neuroendocrine Peptidergic System Disruption Using the AtT20 Pituitary Cell Line as a Model -- Proteomics-Based Method for Risk Assessment of Peroxisome Proliferating Pollutants in the Marine Environment -- Environmental Metabolomics Using 9 H-NMR Spectroscopy -- Detection of Whole Genome Mutation -- Restriction Landmark Genome Scanning for the Detection of Mutations -- Use of the Comet Assay in Environmental Toxicology -- The Micronucleus Assay Determination of Chromosomal Level DNA Damage -- Fluorescence In Situ Hybridization for the Detection of Chromosome Aberrations and Aneuploidy Induced by Environmental Toxicants -- Laboratory Methods for the Detection of Chromosomal Structural Aberrations in Human and Mouse Sperm by Fluorescence In Situ Hybridization -- Determination of Species Diversity -- Assembling DNA Barcodes -- Application of Suppressive Subtractive Hybridization to Uncover the Metagenomic Diversity of Environmental Samples -- 16S rRNA Targeted DGGE Fingerprinting of Microbial Communities -- An Emulsion Polymerase Chain Reaction-Based Method for Molecular Haplotyping.
520			_aEnvironmental genomics seeks to predict how an organism or organisms will respond, at the genetic level, to changes in their external environment. These genome responses are diverse and, as a result, environmental genomics must integrate molecular biology, physiology, toxicology, ecology, systems biology, epidemiology and population genetics into an interdisciplinary research program. Environmental Genomics serves as a manual for an environmental scientist who wishes to embrace genomics in an effort to answer environmental questions. The volume is divided into the sections: gene expression profiling, whole genome and chromosome mutation detection, and methods to assay genome diversity and polymorphisms within a particular environment. The studies presented will reduce the uncertainties associated with environmental risk assessment and provide a systematic framework for determining environmental impact and ensuring human health and the sustainability of natural populations. Environmental Genomics should aid researchers looking to reduce the uncertainties associated with environmental risk assessment and provide a systematic framework for determining environmental impact and ensuring human health and the sustainability of natural populations.
700	1		_aMartin, C. Cristofre _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617377716
776	0	8	_iPrinted edition: _z9781588297778
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-548-0 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2008
999			_c233819 _d233819