000			03571nam a22003615i 4500
001			233866
003			ES-VaUE
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007			cr nn 008mamaa
008			150324s2015 xxu| s |||| 0|eng d
020			_a9781493925223
024	7		_a10.1007/978-1-4939-2522-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aStress Responses _bMethods and Protocols _cedited by Christine M. Oslowski.
250			_a1st edition 2015
264		1	_aNew York, NY _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XI, 246 páginas) _b51 ilustraciones, 28 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1292
505	0		_aMethods for Studying ER Stress and UPR Markers in Human Cells -- Assays for Induction of the Unfolded Protein Response and Selective Activation of the Three Major Pathways -- Assays to Characterize Molecular Chaperone Functions in vitro -- Analysis of Heat Shock Factor Complex in Mammalian HSP70 Promoter -- Immunofluorescence-Based Methods to Monitor DNA End Resection -- Visualizing the Spatiotemporal Dynamics of DNA Damage in Budding Yeast -- Detecting Reactive Oxygen Species by Immunohistochemistry -- Investigating Inflammasome Activation Under Conditions of Cellular Stress and Injury -- Methods for Studying microRNA Functions During Stress -- Measuring Autophagy in Stressed Cells -- Detection of Apoptosis Using Fluorescent Probes -- Measuring Death of Pancreatic Beta Cells in Response to Stress and Cytotoxic T Cells -- Adaptation of the Secretory Pathway in Cancer Through IRE1 Signaling -- Studying Nitrosative Stress in Parkinson's Disease -- Crosstalk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease --  Stress Responses During Ageing: Molecular Pathways Regulating Protein Homeostasis -- Targeting Stress Responses for Regenerative Medicine.
520			_aThis volume focuses on detecting different cellular stresses, measuring pathological consequences within the cell, and investigating the role of cellular stresses in select diseases. In addition, this book reviews the crosstalk between different stress pathways, stress responses during ageing, and targeting stress for regenerative medicine. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.  Authoritative and instructive, Stress Responses: Methods and Protocols seeks to aid scientists to further study multiple stress pathways and outcomes triggered by such stresses. In depth knowledge of cellular stress will eventually lead to the development of novel therapeutics to prevent or treat related diseases.  .
700	1		_aOslowski, Christine M _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493925216
776	0	8	_iPrinted edition: _z9781493925230
776	0	8	_iPrinted edition: _z9781493948482
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2522-3 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2015
999			_c233866 _d233866