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001			233906
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008			100715s2009 xxu| s |||| 0|eng d
020			_a9781607613220
024	7		_a10.1007/978-1-60761-322-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aLipidomics _bVolume 1: Methods and Protocols _cedited by Donald Armstrong.
250			_a1st edition 2009
264		1	_aTotowa, NJ _bHumana Press _c2009
300			_a1 recurso en línea (XIV, 550 páginas) _b143 ilustraciones, 4 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v579
505	0		_aShotgun and Global Lipidomics -- Examination of the Brain Mitochondrial Lipidome Using Shotgun Lipidomics -- Tracking the Glycerophospholipid Distribution of Docosahexaenoic Acid by Shotgun Lipidomics -- Global Analysis of Retina Lipids by Complementary Precursor Ion and Neutral Loss Mode Tandem Mass Spectrometry -- Combining Lipidomics and Proteomics of Human Cerebrospinal Fluids -- Analytical Approaches -- Lipid Profiling Using Two-Dimensional Heteronuclear Single Quantum Coherence NMR -- Capabilities and Drawbacks of Phospholipid Analysis by MALDI-TOF Mass Spectrometry -- Lipidomics of the Red Cell in Diagnosis of Human Disorders -- HPLC/MS/MS-Based Approaches for Detection and Quantification of Eicosanoids -- Brain Phosphoinositide Extraction, Fractionation, and Analysis by MALDI-TOF MS -- Lipidomic Analysis of Biological Samples by Liquid Chromatography Coupled to Mass Spectrometry -- Lipidomic Analysis of Human Meibum Using HPLC-MSn -- Lipid Geographical Analysis of the Primate Macula by Imaging Mass Spectrometry -- A Novel Role for Nutrition in the Alteration of Functional Microdomains on the Cell Surface -- Lipidomic Analysis of Prostanoids by Liquid Chromatography-Electrospray Tandem Mass Spectrometry -- Qualitative and Quantitative Analyses of Phospholipids by LC-MS for Lipidomics -- Determination of Fatty Acid Profiles and TAGs in Vegetable Oils by MALDI-TOF/MS Fingerprinting -- Dynamics of Adipose Tissue Development by 2H2O Labeling -- Analysis of Lipid Particles from Yeast -- Mammalian Fatty Acid Elongases -- Membrane Lipidomics and the Geometry of Unsaturated Fatty Acids From Biomimetic Models to Biological Consequences -- OnLine Ozonolysis Methods for the Determination of Double Bond Position in Unsaturated Lipids -- Comprehensive Quantitative Analysis of Bioactive Sphingolipids by High-Performance Liquid Chromatography-Tandem Mass Spectrometry -- The Use of Charged Aerosol Detection with HPLC for the Measurement of Lipids -- Lipid Maps -- Non-invasive Mapping of Lipids in Plant Tissue Using Magnetic Resonance Imaging -- Mapping the Lipolytic Proteome of Adipose Tissue Using Fluorescent Suicide Inhibitors -- Identifying the Spatial Distribution of Vitamin E, Pulmonary Surfactant and Membrane Lipids in Cells and Tissue by Confocal Raman Microscopy.
520			_aEssential in biological functions like cell signaling and, when disturbed, a likely cause of disease, lipids have proven to be a vital force in cell biology. In Lipidomics: Methods and Protocols, an international panel of experts present a wide variety of reviewed as well as unpublished data on isolation techniques, structural analysis, lipid rafts, lipid trafficking and profiling, biomarkers, lipid peroxidation, biostatistics applied to lipids, software tools, and bioinformatics. These studies range from simple systems, such as in yeast, to complex biological models. Samples used in these studies include: mitochondria, microsomes, endosomal membranes, RBS and plasma membranes, vesicles, caveolae, liposomes, macrophages, meibum, brain, microglia, retina, adipose tissue, keratinocytes, pulmonary surfactant, and hepatic cultures. Volume 1 focuses on shotgun and global lipidomics, analytical approaches, and lipid maps. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include useful introductions to their respective topics, lists of the necessary equipment and materials, step-by-step, readily reproducible laboratory protocols, and authoritative notes on troubleshooting and avoiding common pitfalls. Comprehensive and cutting-edge, Lipidomics: Methods and Protocols will support researchers who wish to increase their utilization of lipidomics, which will certainly lead to more powerful technology, improved diagnostic-prognostic capabilities, and the identification of new valuable products.
700	1		_aArmstrong, Donald _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781607613237
776	0	8	_iPrinted edition: _z9781607613213
776	0	8	_iPrinted edition: _z9781617796463
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-322-0 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2009
999			_c233906 _d233906