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001			233942
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007			cr nn 008mamaa
008			180620s2018 xxu| s |||| 0|eng d
020			_a9781493985524
024	7		_a10.1007/978-1-4939-8552-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aGangliosides _bMethods and Protocols _cedited by Sandro Sonnino, Alessandro Prinetti.
250			_a1st edition 2018
264		1	_aNew York, NY _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XV, 456 páginas) _b101 ilustraciones, 56 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1804
505	0		_aChemical and Physicochemical Properties of Gangliosides -- Gangliosides of the Nervous System -- Scattering Techniques and Ganglioside Aggregates: Laser Light, Neutron and X-Ray Scattering -- Gangliosides in the Immune System: Role of Glycosphingolipids and Glycosphingolipid-Enriched Lipid Rafts in Immunological Functions -- Ganglioside Metabolism and Its Inherited Diseases -- Gangliosides and Tumors -- Anti-Ganglioside Antibodies in Peripheral Nerve Pathology -- Protocols of Glycosyltransferase Assays: Ganglioside Globoside and Lewis-X Intermediate-Lactosylceramide Biosyntheses in Eukeryotic Systems -- Mass Spectrometry of Gangliosides -- Visualization of Brain Gangliosides Using MALDI Imaging Mass Spectrometry -- Immunoelectron Microscopy of Gangliosides -- Nuclear Magnetic Resonance of Gangliosides -- Methods for the Preparation of Anti-Ganglioside Monoclonal Antibodies -- Chemical Synthesis of Gangliosides -- Radioactive Gangliosides for Biological Studies -- Synthesis of Fluorescent Gangliosides -- Synthesis of Photoactivatable and Paramagnetic Gangliosides -- Methods for Assay of Ganglioside Catabolic Enzymes -- Pharmacological Modulation of Glycosphingolipid Metabolism -- Molecular Dynamics of Gangliosides -- Determination of Glycolipid Ligands of Carbohydrate-Binding Proteins Directly on Thin Layer Chromatograms -- Identification of KDN-Gangliosides -- Glycoreplica Peptides.
520			_aThis detailed volume explores methods of examining gangliosides, membrane amphiphilic lipids that are deeply involved in the modulation of the overall properties of cellular membranes, as well as of the functions of membrane-associated proteins. The contents take into account the vital availability of new enzymatic approaches, the knowledge of an incredibly extensive number of glyco-enzymes, and the improvement of multi-genetic analyses. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Gangliosides: Methods and Protocols serves as a valuable guidebook for entering in the vast research world of gangliosides.
700	1		_aSonnino, Sandro _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aPrinetti, Alessandro _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493985517
776	0	8	_iPrinted edition: _z9781493985531
776	0	8	_iPrinted edition: _z9781493993239
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-8552-4 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c233942 _d233942