| 000 | 05643nam a22003615i 4500 | ||
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| 001 | 233957 | ||
| 003 | ES-VaUE | ||
| 005 | 20221220020532.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100301s2008 xxu| s |||| 0|eng d | ||
| 020 | _a9781603270328 | ||
| 024 | 7 |
_a10.1007/978-1-60327-032-8 _2doi |
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| 040 |
_aES-MaUEC _bspa _cES-MaUEC |
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| 245 | 1 | 0 |
_aBacterial Pathogenesis _bMethods and Protocols _cedited by Frank DeLeo, Michael Otto. |
| 250 | _a1st edition 2008 | ||
| 264 | 1 |
_aTotowa, NJ _bHumana Press _c2008 |
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| 300 |
_a1 recurso en línea (XVI, 320 páginas) _b47 ilustraciones, 10 ilustraciones a color |
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| 336 |
_atexto _btxt _2rdacontent |
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| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 347 |
_aarchivo de texto _bPDF |
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| 490 | 0 |
_aMethods in Molecular Biology _x1940-6029 _v431 |
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| 505 | 0 | _aPreface -- Contributors -- List of Color Plates -- I: Mechanisms of Bacterial Pathogenesis -- 1 Isolation and Characterization of LipopolysaccharidesMichael A. Apicella -- 2 Proteomic Analysis of Proteins Secreted by Streptococcus pyogenesMichelle A. Chaussee, Emily J. McDowell, and Michael S. Chaussee -- 3 Proteomic Analysis to Investigate Regulatory Networks in Staphylococcus aureusSusanne Engelmann and Michael Hecker -- 4 Microarray Comparative Genomic Hybridization for the Analysis of Bacterial Population Genetics and EvolutionCaitriona M. Guinane and J. Ross Fitzgerald -- 5 Detection and Inhibition of Bacterial Cell-Cell CommunicationScott A. Rice, Diane McDougald, Michael Givskov, and Staffan Kjelleberg -- 6 A System for Site-Specific Genetic Manipulation of the Relapsing Fever Spirochete Borrelia hermsiiJames M. Battisti, Sandra J. Raffel, and Tom G. Schwan -- 7 Transposon Mutagenesis of the Lyme Disease Agent Borrelia burgdorferiPhilip E. Stewart and Patricia A. Rosa -- 8 The Biofilm Exopolysaccharide Polysaccharide Intercellular Adhesin?A Molecular and Biochemical ApproachCuong Vuong and Michael Otto -- II: Host-Pathogen Interaction -- 9 Analysis of Staphylococcus aureus Gene Expression During PMN PhagocytosisJovanka M. Voyich, Dan E. Sturdevant, and Frank R. DeLeo -- 10 Examining the Vector-Host-Pathogen Interface With Quantitative Molecular ToolsJason E. Comer, Ellen A. Lorange, and B. Joseph Hinnebusch -- 11 Intracellular Localization of Brucella abortus and Francisella tularensis in Primary Murine MacrophagesJean Celli -- 12 Rate and Extent of Helicobacter pylori PhagocytosisLee-Ann H. Allen -- 13 Culture, Isolation, and Labeling of Anaplasma phagocytophilum for Subsequent Infection of Human NeutrophilsDori L. Borjesson -- 14 Ultrastructural Analysis of Bacteria-Host Cell InteractionsDavid W. Dorward -- 15 Infection of Human Monocyte-Derived Macrophages With Coxiella burnetiiJeffrey G. Shannon and Robert A. Heinzen -- 16 Infection of Epithelial Cells With Salmonella entericaOlivia Steele-Mortimer -- 17 Determining the Cellular Targets of Reactive Oxygen Species in Borrelia burgdorferiJulie A. Boylan and Frank C. Gherardini -- III: Animal Models of Bacterial Infection -- 18 Bioluminescent Imaging of Bacterial Biofilm Infections In VivoJagath L. Kadurugamuwa and Kevin P. Francis -- 19 The Cotton Rat as a Model for Staphylococcus aureus Nasal Colonization in Humans: Cotton Rat S. aureus Nasal Colonization ModelJohn F. Kokai-Kun -- 20 A Non-Human Primate Model of Acute Group A Streptococcus PharyngitisPaul Sumby, Anne H. Tart, and James M. Musser -- IV: Identification of Therapeutic Targets and Typing Methods -- 21 Target-Based Antimicrobial Drug DiscoveryLefa E. Alksne and Paul M. Dunman -- 21 Sequence Analysis of the Variable Number Tandem Repeat in Staphylococcus aureus Protein A Gene: spa TypingBarun Mathema, Jose Mediavilla, and Barry N. Kreiswirth. | |
| 520 | _aBacterial infections affect world health today as a leading cause of morbidity and mortality. Pathogenic bacteria routinely command a broad spectrum of niches in the human host, making an understanding of pathogenesis mechanisms crucial to the development of prophylactics and treatment for bacterial diseases. A variety of in vitro methods, in vivo animal model systems and cutting-edge genomics assays have arisen in the effort to study bacterial pathogenesis and identify potential therapeutic targets. In Bacterial Pathogenesis, in-depth methods and state-of-the-art protocols are presented for investigating specific mechanisms of pathogenesis for a wide range of bacteria. This invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections. Up-to-date molecular typing methods for Staphylococcus aureus and a new model of streptococcal pharyngitis in non-human primates are also included. Bacterial Pathogenesis will prove an invaluable collection for microbiologists, immunologists, cell biologists and infectious disease clinicians - and indispensable to all science researchers interested in studying pathogenic bacteria and related disease processes. | ||
| 700 | 1 |
_aDeLeo, Frank _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 700 | 1 |
_aOtto, Michael _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 776 | 0 | 8 |
_iPrinted edition: _z9781617377518 |
| 776 | 0 | 8 |
_iPrinted edition: _z9781588297402 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60327-032-8 _z(usuarios Universidad Europea de Valencia) |
| 942 |
_2lcc _cLE |
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| 988 | _aSpringer_Protocols_2008 | ||
| 999 |
_c233957 _d233957 |
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