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001 233990
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020 _a9781493927272
024 7 _a10.1007/978-1-4939-2727-2
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aGene Therapy of Solid Cancers
_bMethods and Protocols
_cedited by Wolfgang Walther, Ulrike Stein.
250 _a1st edition 2015
264 1 _aNew York, NY
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (XIII, 387 páginas)
_b60 ilustraciones, 30 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1317
505 0 _aAptamer Targeting the ERBB2 Receptor Tyrosine Kinase for Applications in Tumor Therapy -- Gene Gun Her2/neu DNA Vaccination: Evaluation Of Vaccine Efficacy in a Syngeneic Her2/neu Mouse Tumor Model -- MIDGE Technology for the Production of a Fourfold Gene-Modified, Allogenic Cell-Based Vaccine For Cancer Therapy -- Evaluation of Bystander Cell Killing Effects in Suicide Gene Therapy of Cancer: Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis -- Oncoleaking: Use of the Pore-forming Clostridium perfringens Enterotoxin (CPE) for Suicide Gene Therapy -- iCaspase 9 Suicide Gene System -- p53-encoding pDNA Purification by Affinity-Chromatography for Cancer Therapy -- A qRT-PCR Method for Determining the Biodistribution Profile of a miR-34a Mimic -- Design and Selection of Antisense Oligonucleotides Targeting Transforming Growth Factor Beta (TGF-b) Isoform mRNAs for the Treatment of Solid Tumors -- RNA Interference for Antimetastatic Therapy -- STAT3 Decoy ODN Therapy for Cancer -- Oncolytic Viral Therapy using Reovirus -- Use of GLV-1h68 for Vaccinia Virotherapy and Monitoring -- Back To The Future: Are Tumor-Targeting Bacteria The Next Generation Cancer Therapy? --  Ethics of Cancer Gene Transfer Clinical Research -- Planning an Academic Clinical Trial -- Production of Plasmid DNA as Pharmaceutical -- Minicircle - Next Generation DNA Vectors for Vaccination -- A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular Carcinoma -- Antiangiogenic Metargidin Peptide (AMEP) Gene Therapy in Disseminated Melanoma -- Clinical Evaluation of ErbB-targeted CAR T-cells, Following Intra-Cavity Delivery in Patients with ErbB-Expressing Solid Tumors.    .
520 _aThis volume provides insight into recent developments on experimental and clinical strategies for cancer gene therapy. Gene Therapy of Solid Cancers: Methods and Protocols guides readers through protocols on gene therapeutic strategies in combination with helpful technical notes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Concise and easy-to-use, Gene Therapy of Solid Cancers: Methods and Protocols aims to ensure successful results in the further study of this vital field.
700 1 _aWalther, Wolfgang
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aStein, Ulrike
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493927265
776 0 8 _iPrinted edition:
_z9781493927289
776 0 8 _iPrinted edition:
_z9781493955923
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2727-2
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2015
999 _c233990
_d233990