000			03859nam a22003615i 4500
001			234113
003			ES-VaUE
005			20221220020541.0
007			cr nn 008mamaa
008			160829s2016 xxu| s |||| 0|eng d
020			_a9781493956203
024	7		_a10.1007/978-1-4939-5620-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aRodent Models of Stroke _cedited by Ulrich Dirnagl.
250			_a2nd edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XII, 338 páginas) _b61 ilustraciones, 54 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v120
505	0		_aFrom Bedside to Bench: How Clinical Reality Should Instruct Stroke Modeling -- How to Avoid Bumping into the Translational Roadblock -- Modeling Focal Cerebral Ischemia in Rodents: Introduction and Overview -- Focal Cerebral Ischemia in the Mouse and Rat by Intraluminal Suture -- Focal Ischemia Models: Middle Cerebral Artery Occlusion Induced by Electrocoagulation, Occluding devices and Endothelin-1 -- Mouse Model of in situ Thromboembolic Stroke and Reperfusion -- Photochemical Models of Focal Brain Ischemia -- Housing in an Enriched Environment - A Tool to Study Functional Recovery after Experimental Stroke -- Modeling Risk Factors and Confounding Effects in Stroke -- Effect of Anesthesia in Stroke Models -- Non-invasive Brain Imaging in Small Animal Stroke Models: MRI, PET and SPECT -- Non-invasive Optical Imaging in Rodent Models of Stroke -- Behavioral Testing in Rodent Models of Stroke, Part I -- Behavioral Testing in Rodent Models of Stroke -Part II -- Combining Classical Comprehensive With Ethological Based, High Throughput Automated Behavioral Phenotyping for Rodent Models of Stroke -- Histology and Infarct Volume Determination in Rodent Models of Stroke -- Ethics of Modeling of Cerebral Ischemia in Small Animals -- Quality Control and Standard Operating Procedures -- Statistics in Experimental Stroke Research: From Sample Size Calculation to Data Description and Significance Testing -- Complexities, Confounders, and Challenges in Experimental Stroke Research: A Checklist for Researchers and Reviewers.
520			_aThis second edition provides updated and expanded chapters that critically address the issues or rodent stroke modeling, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. Rodent Models of Stroke, Second Edition aims to help its readers understand the limitations and the opportunities of modeling stroke in rodents and enable them to conduct experiments which will not only improve our understanding of the pathophysiology of this devastating disorder but also serve as the basis for developing new highly effective treatments. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Rodent Models of Stroke, Second Edition provides authoritative reviews of the most commonly used, well-honed approaches in the field today. .
700	1		_aDirnagl, Ulrich _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493956180
776	0	8	_iPrinted edition: _z9781493956197
776	0	8	_iPrinted edition: _z9781493981670
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-5620-3 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2016
999			_c234113 _d234113