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001			234130
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007			cr nn 008mamaa
008			171004s2017 xxu| s |||| 0|eng d
020			_a9781493972746
024	7		_a10.1007/978-1-4939-7274-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aStatistical Human Genetics _bMethods and Protocols _cedited by Robert C. Elston.
250			_a2nd edition 2017
264		1	_aNew York, NY _bSpringer International Publishing _c2017
300			_a1 recurso en línea (XII, 689 páginas) _b114 ilustraciones, 64 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1666
505	0		_aStatistical Genetic Terminology -- Identification of Genotype Errors -- Detecting Pedigree Relationship Errors -- Identifying Cryptic Relationships -- Estimating Allele Frequencies -- Testing Departure from Hardy-Weinberg Proportions -- Estimating Disequilibrium Coefficients -- Detecting Familial Aggregation -- Estimating Heritability from Twin Studies -- Estimating Heritability from Nuclear Family and Pedigree Data -- Correcting for Ascertainment -- Segregation Analysis using the Unified Model -- Design Considerations for Genetic Linkage and Association Studies -- Model-based Linkage Analysis of a Quantitative Trait -- Model-based Linkage Analysis of a Binary Trait -- Model-free Linkage Analysis of a Quantitative Trait -- Model-free Linkage Analysis of a Binary Trait -- Single Marker Association Analysis for Unrelated Samples -- Single Marker Family-based Association Analysis Conditional on Parental Information -- Single Marker Family-based Association Analysis not Conditional on Parental Information -- Calibrating Population Stratification in Association Analysis -- Cross-phenotype Association Analysis using Summary Statistics from GWAS -- Haplotype Inference -- Multi-SNP Haplotype Analysis Methods for Association Analysis -- The Analysis of Ethnic Mixtures -- Detecting Multiethnic Rare Variants -- Identifying Gene Interaction Networks -- Structural Equation Modeling -- Mendelian Randomization -- Preprocessing and Quality Control for Whole Genome Sequences from the Illumina HiSeq X Platform -- Statistical Approaches for Processing and Analyzing Microbiome Data.
520			_aThe aim of this volume is to make computer programs for analyzing human genetic data more easily accessible to the beginner.Statistical Human Genetics: Methods and Protocols, Second Edition provides updated and new chapters detailing genetic terms, analysis software, and how to interpret the program outputs. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, step-by-step instructions, and tips on troubleshooting and avoiding known pitfalls.  The purpose of Statistical Human Genetics: Methods and Protocols, Second Edition is to ensure successful and meaningful results in the fast-growing field of genetic epidemiology.
700	1		_aElston, Robert C _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493972739
776	0	8	_iPrinted edition: _z9781493972753
776	0	8	_iPrinted edition: _z9781493984381
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7274-6 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2017
999			_c234130 _d234130