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001			234133
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008			171017s2018 xxu| s |||| 0|eng d
020			_a9781493973521
024	7		_a10.1007/978-1-4939-7352-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aCharacterization of Nanoparticles Intended for Drug Delivery _cedited by Scott E. McNeil.
250			_a2nd edition 2018
264		1	_aNew York, NY _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XII, 256 páginas) _b72 ilustraciones, 40 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1682
505	0		_aEvaluating Nanomedicines: Obstacles and Advancements -- Detection of Bacterial Contamination in Nanoparticle Formulations by Agar Plate Test -- Considerations and Some Practical Solutions to Overcome Nanoparticle Interference with LAL Assays and to Avoid Endotoxin Contamination in Nanoformulations -- Elemental Analysis in Biological Matrices Using ICP-MS -- PEG Quantitation Using Reversed Phase High Performance Liquid Chromatography and Charged Aerosol Detection -- Quantitation of Surface Coating on Nanoparticles Using Thermogravimetric Analysis -- Immunoelectron Microscopy for Visualization of Nanoparticles -- Imaging of Liposomes by Transmission Electron Microscopy -- Updated Method for In Vitro Analysis of Nanoparticle Hemolytic Properties -- In Vitro Assessment of Nanoparticle Effects on Blood Coagulation -- In Vitro Analysis of Nanoparticle Effects on the Zymosan Uptake by Phagocytic Cells -- Assessing NLRP3 Inflammasome Activation by Nanoparticles -- Analysis of Complement Activation by Nanoparticles -- Methods for Analysis of Nanoparticle Immunosuppressive Properties In Vitro and In Vivo -- Analysis of Pro-Inflammatory Cytokine and Type II Interferon Induction by Nanoparticles -- Analysis of Nanoparticle Adjuvant Properties In Vivo -- In Vitro and In Vivo Methods for Analysis of Nanoparticle Potential to Induce Delayed Type Hypersensitivity Reactions -- Autophagy Monitoring Assay II: Imaging Autophagy Induction in LLC-PK1 Cells Using GFP-LC3 Protein Fusion Construct -- Improved Ultrafiltration Method to Measure Drug Release from Nanomedicines Utilizing a Stable Isotope Tracer -- Designing an In Vivo Efficacy Study of Nanomedicines for Preclinical Tumor Growth Inhibition.
520			_aThis second edition volume expands on the first edition by providing up-to-date protocols to characterize nanomaterials used as drug delivery agents. The chapters in this book are divided into 5 parts and cover topics such as: advances and obstacles in nanomedicine research; methods to test sterility and endotoxin, physicochemical features, immunological effects, drug release, and in vivo efficacy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Characterization of Nanoparticles Intended for Drug Delivery, Second Edition is a valuable tool for researchers and pharmaceutical and biotechnology developers who are evaluating the clinical potential of nanomedicines in preclinical studies.>.
700	1		_aMcNeil, Scott E _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493973507
776	0	8	_iPrinted edition: _z9781493973514
776	0	8	_iPrinted edition: _z9781493984602
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7352-1 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c234133 _d234133