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008			140204s2014 xxu| s |||| 0|eng d
020			_a9781493903269
024	7		_a10.1007/978-1-4939-0326-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aSystemic Lupus Erythematosus _bMethods and Protocols _cedited by Paul Eggleton, Frank J. Ward.
250			_a1st edition 2014
264		1	_aNew York, NY _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XVII, 263 páginas) _b35 ilustraciones, 22 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1134
505	0		_aPathology of Systemic Lupus Erythematosus - The Challenges Ahead -- The Lupus Biomarker Odyssey: One Experience -- Detection of Anti Nuclear Antibodies in SLE -- Tests for Circulating Immune Complexes -- Methods for Measuring Antibody Dependent Cell-Mediated Cytotoxicity in vitro -- Recombinant Antibody Microarray for Profiling the Serum Proteome of SLE -- Bi-functional Antibody Fragment-based Fusion Proteins for the Targeted Elimination of Pathogenic T-cell Subsets -- TLC Immunostaining for Detection of "Anti-Phospholipid" Antibodies -- Induced Murine Models of Systemic Lupus Erythematosus -- Measuring Interferon Alpha and other Cytokines in SLE -- Detection of SLE antigens in Neutrophils Extracellular Traps (NETs) -- Detection and Characterization of Autoantibodies Against Modified Self-proteins in SLE Sera after Exposure to Reactive Oxygen and Nitrogen Species -- Generation of Self-peptides to Treat Systemic Lupus Erythematosus -- Measurement of Malondialdehyde, Glutathione and Glutathione Peroxidase in SLE Patients -- Evaluating a Particular Circulating MicroRNA Species from an SLE Patient using Stem Loop qRT-PCR -- Microarray Technology for Analysis of MicroRNA Expression in Renal Biopsies of Lupus Nephritis Patients. Laboratory Tests for the Antiphospholipid Syndrome -- Isolation, Polarisation and Expansion of CD4+ T Helper Cell Lines and Clones using Magnetic Beads -- Meta-analysis as a Diagnostic Tool for Predicting Disease Onset and/or Activity in Systemic Lupus Erythematosus.
520			_aSystemic Lupus Erythematosus: Methods and Protocols describes a number of genetic, biochemical and immunological techniques. These techniques provide an advancing understanding of the pathology, breakdown of the immune system, and therapeutic challenges of SLE in both humans and animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Systemic Lupus Erythematosus: Methods and Protocols  appeals to biomedical and clinical scientists in a number of pathology disciplines at the doctoral and post-doctoral level.
700	1		_aEggleton, Paul _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aWard, Frank J _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493903276
776	0	8	_iPrinted edition: _z9781493903252
776	0	8	_iPrinted edition: _z9781493952625
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-0326-9 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2014
999			_c234251 _d234251