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020 _a9781493967988
024 7 _a10.1007/978-1-4939-6798-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aModeling Peptide-Protein Interactions
_bMethods and Protocols
_cedited by Ora Schueler-Furman, Nir London.
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XI, 311 páginas)
_b87 ilustraciones, 68 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1561
505 0 _aThe Usage of ACCLUSTER for Peptide Binding Site Prediction -- Detection of Peptide-Binding Sites on Protein Surfaces using the Peptimap Server -- Peptide Sub-Optimal Conformation Sampling for the Prediction of Protein-Peptide Interactions -- Template-Based Prediction of Protein-Peptide Interactions by Using GalaxyPepDock -- Application of the ATTRACT Coarse-Grained Docking and Atomistic Refinement for Predicting Protein-Peptide Interactions -- Highly Flexible Protein-Peptide Docking Using CABS-Dock -- AnchorDock for Blind Flexible Docking of Peptides to Proteins -- Information-Driven, Ensemble Flexible Peptide Docking Using HADDOCK -- Modeling Peptide-Protein Structure and Binding Using Monte Carlo Sampling Approaches: Rosetta FlexPepDock & FlexPepBind -- Flexible Backbone Methods for Predicting and Designing Peptide Specificity -- SImplifying the Design of Protein-Peptide Interaction Specificity with Sequence-Based Representations of Atomistic Models -- Binding Specificity Profiles from Computational Peptide Screening -- Enriching Peptide Libraries for Binding Affinity and Specificity through Computationally Directed Library Design -- Investigating Protein-Peptide Interactions Using the Schrödinger Computational Suite -- Identifying Loop-Mediated Protein-Protein Interactions using LoopFinder -- Protein-Peptide Interaction Design: PepCrawler and PinaColada -- Modeling and Design of Peptidomimetics to Modulate Protein-Protein Interactions.
520 _aThis volume covers an array of techniques available for studying peptide-protein docking and design. The book is divided into four sections: peptide binding site prediction; peptide-protein docking; prediction and design of peptide binding specificity; and the design of inhibitory peptides. The chapters in Modeling Peptide-Protein Interactions: Methods and Protocols cover topics such as the usage of ACCLUSTER and PeptiMap for peptide binding site prediction; AnchorDock and ATTRACT for blind, flexible docking of peptides to proteins; flexible peptide docking using HADDOCK and FlexPepDock; identifying loop-mediated protein-protein interactions using LoopFinder; and protein-peptide interaction design using PinaColada. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary details for successful application of the different approaches and step-by-step, readily reproducible protocols, as well as tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Modeling Peptide-Protein Interactions: Methods and Protocols provides a diverse and unified overview of this rapidly advancing field of major interest and applicability.
700 1 _aSchueler-Furman, Ora
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aLondon, Nir
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493967964
776 0 8 _iPrinted edition:
_z9781493967971
776 0 8 _iPrinted edition:
_z9781493983025
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6798-8
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2017
999 _c234291
_d234291