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020 _a9781592595983
024 7 _a10.1385/0896033805
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aTumor Marker Protocols
_cedited by Margaret Hanausek, Zbigniew Walaszek.
250 _a1st edition 1998
264 1 _aTotowa, NJ
_bHumana Press
_c1998
300 _a1 recurso en línea (XIV, 500 páginas)
_b
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Medicine
_x1940-6037
_v14
505 0 _aMultiple Markers: Principles and Guidelines -- Integrating Multiple Clinical Tests to Increase Predictive Power -- Statistical Considerations in the Analysis of Tumor Markers -- Selection and Development of Biomarkers for Bladder Cancer -- Clinical Application of Tissue and Serum Markers in Breast Cancer -- Immunodiagnosls of Cancer: Serum and Tissue Markers -- Serum and Tissue Biomarkers in the Prognosis and Treatment of Breast Cancer -- The Oncofetal Protein p65 in Breast Cancer Detection -- Determination of Tumor Ferritin Concentration in Breast Cancer -- Immunodiagnosis of Childhood Malignancies -- Immunohistochemical Evaluation of Biomarkers in Prostatic and Colorectal Neoplasia -- Factors Affecting Immunohistochemical Evaluation of Biomarker Expression in Neoplasia -- Instrumentation, Accuracy, and Quality Control Issues in Development of Quantitative Fluorescence-Image Analysis (QFIA) -- Cytogenetic Markers -- Cytogenetics as a Diagnostic Aid for Childhood Hematologic Disorders -- Preparation of Metaphase Chromosomes for Cytogenetic Analysis -- Chromosome Staining and Banding Techniques -- Fluorescence In Situ Hybridization to Chromosomes -- Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction -- Molecular Markers -- Applications of Tissue Microdissection in Molecular Pathology -- EWS Gene Fusions as Diagnostic Markers in Sarcomas -- p53 Detection in Breast Cancer -- Use of the Polymerase Chain Reaction Technique to Detect the t(14;18) Translocation in Lymphoid Tissue -- Detection of ras Gene Mutations Using Oligonucleotide Ligation Technology -- Detection of Prostate-Cancer Cells in Blood and Bone Marrow by RT-PCR -- Quantitative, Competitive RT-PCR Analysis of Biomarkers in the Study of Neoplasia -- Differential Display to Define Molecular Markers and Genes That Mediate Malignancy -- Miscellaneous Markers and Early Detection of Cancer -- Transforming Growth Factor Beta -- Anti-HMdU Autoantibodies in Human Sera as a Biomarker of Cancer Risk -- A Scientific Basis for Cancer Prevention -- Aberrant Crypt Foci System to Study Cancer Preventive Agents in the Colon -- Strain-Dependent Differences in the Expression of the Oncofetal Protein p65 in Mice Susceptible and Resistant to Chemical Carcinogenesis -- d-Glucaric Acid as a Prospective Tumor Marker.
520 _aThis much-needed collection of Tumor Marker Protocols presents cutting-edge methods for the detection and discovery of new cancer markers, particularly molecular tumor markers. Each method is fully described by a hands-on expert who uses it regularly in the laboratory and has perfected it to a high degree of ready reproducibility. The book also places special emphasis on statistical considerations in the analysis of tumor markers, recent discoveries in the field of serum and tissue marker proteins, cytogenetic markers, molecular markers, and markers for the early detection of cancer. Tumor Marker Protocols offers many promising opportunities for transferring new technologies from the realm of basic science to that of clinical practice. The well-honed procedures detailed here will enable cancer researchers and clinical oncologists alike to realize the promise of these powerful new diagnostic strategies for the detection, therapy, and successful prevention of cancer.
700 1 _aHanausek, Margaret
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWalaszek, Zbigniew
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781617370199
776 0 8 _iPrinted edition:
_z9780896033801
776 0 8 _iPrinted edition:
_z9781489942517
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/0896033805
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_1998
999 _c234301
_d234301