000			03522nam a22003615i 4500
001			234333
003			ES-VaUE
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007			cr nn 008mamaa
008			171108s2018 xxu| s |||| 0|eng d
020			_a9781493974566
024	7		_a10.1007/978-1-4939-7456-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aSystems Biology _cedited by Mariano Bizzarri.
250			_a1st edition 2018
264		1	_aNew York, NY _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XVII, 364 páginas) _b102 ilustraciones, 83 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1702
505	0		_aConceptual Challenges in the Theoretical Foundations of Systems Biology -- An Integrative Approach toward Biology, Organisms, and Cancer -- Conceptual Challenges of the Systemic Approach in Understanding Cell Differentiation -- A Primer on Mathematical Modeling in the Study of Organisms and their Parts -- The Search for System's Parameters -- Inverse Problems in Systems Biology: A Critical Review -- Systems Biology Approach and Mathematical Modeling for Analyzing Phase-space Switch during Epithelial-mesenchymal Transition -- Parameters Estimation in Phase-space Landscape Reconstruction of Cell Fate; A Systems Biology Approach -- Complexity of Biochemical and Genetic Responses Reduced using Simple Theoretical Models -- Systems Biology Modelling of Non-linear Cancer Dynamics -- Endogenous Molecular-cellular Network Cancer Theory: A Systems Biology Approach -- A Network-based Integrative Workflow to Unravel Mechanisms Underlying Disease Progression -- Spatiotemporal Fluctuation Analysis of Molecular Diffusion Laws in Live-cell Membranes -- A Method for Cross-species Visualization and Analysis of RNA-sequence Data -- Multi Agent Simulations of Population Behavior (A Promising Tool for Systems Biology) -- Metabolomics: Challenges and Opportunities in Systems Biology Studies -- Systems Biology-driven Hypotheses Tested In Vivo: The Need to Advancing Molecular Imaging Tools. .
520			_aThis volume focuses on methodological aspects of systems biology in order to provide a new theoretical approach with a robust and tailored experimental support. Chapters detail mathematical modeling, methodological issues, modulation of the collective behavior, metabolic, dynamic profiling, and quantitative morphological studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Systems Biology aims to ensure successful results in the further study of this vital field.
700	1		_aBizzarri, Mariano _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493974559
776	0	8	_iPrinted edition: _z9781493974573
776	0	8	_iPrinted edition: _z9781493984916
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7456-6 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2018
999			_c234333 _d234333