| 000 | 02718nam a22003615i 4500 | ||
|---|---|---|---|
| 001 | 234388 | ||
| 003 | ES-VaUE | ||
| 005 | 20221220020559.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100301s1996 xxu| s |||| 0|eng d | ||
| 020 | _a9781592595853 | ||
| 024 | 7 |
_a10.1385/0896033058 _2doi |
|
| 040 |
_aES-MaUEC _bspa _cES-MaUEC |
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| 245 | 1 | 0 |
_aAntisense Therapeutics _cedited by Sudhir Agrawal. |
| 250 | _a1st edition 1996 | ||
| 264 | 1 |
_aTotowa, NJ _bHumana Press _c1996 |
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| 300 |
_a1 recurso en línea (XIII, 277 páginas) _b |
||
| 336 |
_atexto _btxt _2rdacontent |
||
| 337 |
_aelectrónico _bc _2rdamedia |
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| 338 |
_arecurso electrónico _bcr _2rdacarrier |
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| 347 |
_aarchivo de texto _bPDF |
||
| 490 | 0 |
_aMethods in Molecular Medicine _x1940-6037 _v1 |
|
| 505 | 0 | _aHistory of Antisense Oligonucleotides -- Pharmacology of Antisense Therapeutic Agents -- Antisense Efficacy -- Antisense Blockade of Expression -- Antisense Tumor Therapy -- Antisense Inhibition of Protein Synthesis and Function -- c-Myb in Smooth Muscle Cells -- Antisense Therapy of Hepatitis B Virus Infection -- Antisense-Mediated Inhibition of Protein Synthesis -- Antisense rel A in Cancer -- Continuous Infusion of Antisense Phosphorothioate Therapeutics -- Protein Kinase-A Directed Antisense Therapy of Tumor Growth In Vivo -- Antisense Therapeutics in the Central Nervous System -- Comparative Pharmacokinetics of Antisense Oligonucleotides. | |
| 520 | _aLeading researchers offer an authoritative survey and analysis of the latest findings on the rapid development of antisense oligonucleotides therapeutic and their application in various in vivo model systems. The book's high-profile contributors provide timely accounts of their state-of-the-art strategies, discussing such topics as the synthesis and purification of oligonucleotides, their selection for a particular gene target, different methods of administration, and the use of various cell lines and cell culture systems. They also examine questions of cellular uptake, in vitro biological activity, in vivo biological activity, the pharmacology and pharmacokinetics of oligonucleotides, and the application of oligonucleotides to the central nervous system. | ||
| 700 | 1 |
_aAgrawal, Sudhir _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
|
| 776 | 0 | 8 |
_iPrinted edition: _z9781489940841 |
| 776 | 0 | 8 |
_iPrinted edition: _z9780896033054 |
| 776 | 0 | 8 |
_iPrinted edition: _z9781489940834 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/0896033058 _z(usuarios Universidad Europea de Valencia) |
| 942 |
_2lcc _cLE |
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| 988 | _aSpringer_Protocols_1996 | ||
| 999 |
_c234388 _d234388 |
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