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020 _a9781493935789
024 7 _a10.1007/978-1-4939-3578-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aStatistical Genomics
_bMethods and Protocols
_cedited by Ewy Mathé, Sean Davis.
250 _a1st edition 2016
264 1 _aNew York, NY
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XI, 418 páginas)
_b113 ilustraciones, 85 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1418
505 0 _aOverview of Sequence Data Formats -- Integrative Exploratory Analysis of Two or More Genomic Datasets -- Study Design for Sequencing Studies -- Genomic Annotation Resources in R/Bioconductor -- The Gene Expression Omnibus Database -- A Practical Guide to the Cancer Genome Atlas (TCGA) -- Working with Oligonucleotide Arrays -- Meta-Analysis in Gene Expression Studies -- Practical Analysis of Genome Contact Interaction Experiments -- Quantitative Comparison of Large-Scale DNA Enrichment Sequencing Data -- Variant Calling From Next Generation Sequence Data -- Genome-Scale Analysis of Cell-Specific Regulatory Codes Using Nuclear Enzymes -- NGS-QC Generator: A Quality Control System for ChIP-seq and Related Deep Sequencing-Generated Datasets -- Operating on Genomic Ranges Using BEDOPS -- GMAP and GSNAP for Genomic Sequence Alignment: Enhancements to Speed, Accuracy, and Functionality -- Visualizing Genomic Data using Gviz and Bioconductor -- Introducing Machine Learning Concepts with WEKA -- Experimental Design and Power Calculation for RNA-Seq Experiments -- It's DE-licious: A Recipe for Differential Expression Analyses of RNA-Seq Experiments Using Quasi-Likelihood Methods in EdgeR.
520 _aThis volume expands on statistical analysis of genomic data by discussing cross-cutting groundwork material, public data repositories, common applications, and representative tools for operating on genomic data. Statistical Genomics: Methods and Protocols is divided into four sections. The first section discusses overview material and resources that can be applied across topics mentioned throughout the book. The second section covers prominent public repositories for genomic data. The third section presents several different biological applications of statistical genomics, and the fourth section highlights software tools that can be used to facilitate ad hoc analysis and data integration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible analysis protocols, and tips on troubleshooting and avoiding known pitfalls. Through and practical, Statistical Genomics: Methods and Protocols, explores a range of both applications and tools and is ideal for anyone interested in the statistical analysis of genomic data.
700 1 _aMathé, Ewy
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aDavis, Sean
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493935765
776 0 8 _iPrinted edition:
_z9781493935772
776 0 8 _iPrinted edition:
_z9781493980833
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3578-9
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2016
999 _c234400
_d234400