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007			cr nn 008mamaa
008			150930s2016 xxu| s |||| 0|eng d
020			_a9781493929962
024	7		_a10.1007/978-1-4939-2996-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aProcess Simulation and Data Modeling in Solid Oral Drug Development and Manufacture _cedited by Marianthi G. Ierapetritou, Rohit Ramachandran.
250			_a1st edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (X, 393 páginas) _b131 ilustraciones, 96 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aApplications of Modeling in Oral Solid Dosage Form Development and Manufacturing -- Population Balance Models for Pharmaceutical Processes -- A Quantitative Approach to Understand Raw Material Variability -- Discrete Element Modeling of Solid Dosage Manufacturing Processes -- A Procedure for Developing Quantitative Near Infrared (NIR) Methods for Pharmaceutical Products -- Advanced Process Decision Making Using Multivariate Latent Variable Methods -- Advanced Control of Continuous Pharmaceutical Tablet Manufacturing Processes -- Mathematical Tools for the Quantitative Definition of a Design Space -- Optimization Methodologies for the Production of Pharmaceutical Products -- An Overview of Pharmaceutical Manufacturing for Solid Dosage Forms.
520			_aThis thorough volume aims to provide pharmaceutical engineers with an introduction to the current state of the art in modeling and simulation of pharmaceutical processes and to summarize a number of practical applications of relevant methodologies in drug product development. Chapters include explorations of simulation and modeling methodologies, data collection and analysis, development of novel sensing techniques, development and integration of individual unit models, optimization approaches for data-based models, design space evaluation techniques, informatics-based methodologies, and emerging topics in pharmaceutical process development. As a part of the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and implementation advice that will make the transition into the laboratory as smooth as possible.   Authoritative and cutting edge, Process Simulation and Data Modeling in Solid Oral Drug Development and Manufacture seeks to promote research into process systems methodologies and their application in pharmaceutical product and process development, which will undoubtedly become an increasingly important area in the future.
700	1		_aIerapetritou, Marianthi G _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aRamachandran, Rohit _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493929955
776	0	8	_iPrinted edition: _z9781493929979
776	0	8	_iPrinted edition: _z9781493949960
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2996-2 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2016
999			_c234473 _d234473