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020 _a9781617790270
024 7 _a10.1007/978-1-61779-027-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aBioinformatics for Omics Data
_bMethods and Protocols
_cedited by Bernd Mayer.
250 _a1st edition 2011
264 1 _aTotowa, NJ
_bHumana Press
_c2011
300 _a1 recurso en línea (XII, 584 páginas)
_b90 ilustraciones, 2 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v719
505 0 _aOmics Technologies, Data, and Bioinformatics Principles -- Data Standards for Omics Data: The Basis of Data Sharing and Reuse -- Omics Data Management and Annotation -- Data and Knowledge Management in Cross-Omics Research Projects -- Statistical Analysis Principles for Omics Data -- Statistical Methods and Models for Bridging Omics Data Levels -- Analysis of Time Course Omics Datasets -- The Use and Abuse of -Omes -- Computational Analysis of High Throughput Sequencing Data -- Analysis of Single Nucleotide Polymorphisms in Case-Control Studies -- Bioinformatics for Copy Number Variation Data -- Processing ChIP-chip Data: From the Scanner to the Browser -- Insights Into Global Mechanisms and Disease by Gene Expression Profiling -- Bioinformatics for RNomics -- Bioinformatics for Qualitative and Quantitative Proteomics -- Bioinformatics for Mass Spectrometry-Based Metabolomics -- Computational Analysis Workflows for Omics Data Interpretation -- Integration, Warehousing, and Analysis Strategies of Omics Data -- Integrating Omics Data for Signaling Pathways, Interactome Reconstruction, and Functional Analysis -- Network Inference from Time-Dependent Omics Data -- Omics and Literature Mining -- Omics-Bioinformatics in the Context of Clinical Data -- Omics-Based Identification of Pathophysiological Processes -- Data Mining Methods in Omics-Based Biomarker Discovery -- Integrated Bioinformatics Analysis for Cancer Target Identification -- Omics-Based Molecular Target and Biomarker Identification.
520 _aPresenting an area of research that intersects with and integrates diverse disciplines, including molecular biology, applied informatics, and statistics, among others, Bioinformatics for Omics Data: Methods and Protocols collects contributions from expert researchers in order to provide practical guidelines to this complex study.  Divided into three convenient sections, this detailed volume covers central analysis strategies, standardization and data-management guidelines, and fundamental statistics for analyzing Omics profiles, followed by a section on bioinformatics approaches for specific Omics tracks, spanning genome, transcriptome, proteome, and metabolome levels, as well as an assortment of examples of integrated Omics bioinformatics applications, complemented by case studies on biomarker and target identification in the context of human disease.  Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and accessible, Bioinformatics for Omics Data: Methods and Protocols serves as an ideal guide to scientists of all backgrounds and aims to convey the appropriate sense of fascination associated with this research field.
700 1 _aMayer, Bernd
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781617790263
776 0 8 _iPrinted edition:
_z9781617790287
776 0 8 _iPrinted edition:
_z9781493957804
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-027-0
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2011
999 _c234490
_d234490