000			04561nam a22003855i 4500
001			234532
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007			cr nn 008mamaa
008			100301s2003 xxu| s |||| 0|eng d
020			_a9781592593729
024	7		_a10.1385/1592593720 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aProstate Cancer Methods and Protocols _cedited by Pamela J. Russell, Paul Jackson, Elizabeth A. Kingsley.
250			_a1st edition 2003
264		1	_aTotowa, NJ _bHumana Press _c2003
300			_a1 recurso en línea (XII, 403 páginas) _b
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Medicine _x1940-6037 _v81
505	0		_aEpidemiological Investigation of Prostate Cancer -- Human Prostate Cancer Cell Lines -- Growth of Prostatic Epithelial and Stromal Cells In Vitro -- Prostate Epithelial Stem Cell Isolation and Culture -- Generation of Immortal Human Prostate Cell Lines for the Study of Prostate Cancer -- Spheroids of Prostate Tumor Cell Lines -- Animal Models of Prostate Cancer -- Transgenic Mouse Models for Prostate Cancer -- In Vivo Models of Human Prostate Cancer Bone Metastasis -- Effects of Fixation on Tissues -- Background, Methods, and Protocols for the Histopathological Diagnosis of Prostate Carcinoma -- Realizing the Potential of Ejaculate/Seminal Fluid in Detecting and Predicting Natural History -- Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival Tissue Samples -- Production and Characterization of Antipeptide Kallikrein 4 Antibodies -- The Androgen Receptor CAG Repeat and Prostate Cancer Risk -- Studies on Androgen Receptor Mutations and Amplification in Human Prostate Cancer -- Proteomics in the Analysis of Prostate Cancer -- Application of Gene Microarrays in the Study of Prostate Cancer -- Enhancer Trap Method Using a Green Fluorescent Protein Reporter Plasmid for Cloning Tissue-Specific Enhancers Active in Prostate Cells -- Targeted Alpha Therapy of Prostate Cancer -- Phenotypic and Functional Differences of Dendritic Cells Generated Under Different In Vitro Conditions -- Flavonoid Compounds in the Prevention and Treatment of Prostate Cancer.
520			_aWith the prostate as the second leading site of cancer among males in Western society, the need to know why certain prostate cancers remain localized while others become aggressive and metastasize has become critical for the care of patients. In Prostate Cancer Methods and Protocols, leading investigators present basic and advanced molecular methods that reveal those markers essential for more accurate diagnoses of specific diseases, and in developing new treatment strategies. The techniques range from in vitro methods to in vivo models of prostate cancer. New methods for the accurate diagnosis of prostate cancer are also offered, including histological assessment, studies of cells in semen, and methylation analysis of the GSTpi, a potential prostate cancer-specific marker. Additional approaches, including proteome and microarray analyses, address such issues as assessing changes in the androgen receptor and studying the enzymes secreted by prostate cancer cells. New strategies for the treatment of refractory disease cover the role of flavonoids, targeted alpha therapy, methods for implementing immune therapy, and prostate-specific gene therapy. Each method is described in step-by-step detail to ensure successful results. Comprehensive and cutting-edge, Prostate Cancer Methods and Protocols provides access to the many powerful tools needed by scientists engaged in prostate cancer research today, as well as up-to-date reviews on several key aspects of the disease.
700	1		_aRussell, Pamela J _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aJackson, Paul _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aKingsley, Elizabeth A _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781489938503
776	0	8	_iPrinted edition: _z9780896039780
776	0	8	_iPrinted edition: _z9781489938497
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592593720 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2003
999			_c234532 _d234532