000			03651nam a22003615i 4500
001			234534
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008			100806s2010 xxu| s |||| 0|eng d
020			_a9781607618065
024	7		_a10.1007/978-1-60761-806-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aTissue Microarrays _bMethods and Protocols _cedited by Ronald Simon.
250			_a1st edition 2010
264		1	_aTotowa, NJ _bHumana Press _c2010
300			_a1 recurso en línea (X, 193 páginas) _b47 ilustraciones, 4 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v664
505	0		_aApplications of Tissue Microarray Technology -- Quality Aspects of TMA Analysis -- Representativity of TMA Studies -- Recipient Block TMA Technique -- Protocol for Constructing Tissue Arrays by Cutting Edge Matrix Assembly -- Hypodermic Needle Without Recipient Paraffin Block Technique -- Resin Technologies: Construction and Staining of Resin TMA's -- Tissue Microarrays from Frozen Tissues-OCT Technique -- An Alternative Technology to Prepare Tissue Microarray Using Frozen Tissue Samples -- Building "Tissue" Microarrays from Suspension Cells -- Tissue Microarrays from Biopsy Specimens -- Immunohistochemical Analysis of Tissue Microarrays -- DNA Copy Number Analysis on Tissue Microarrays -- RNA Expression Analysis on Formalin-Fixed Paraffin-Embedded Tissues in TMA Format by RNA In Situ Hybridization -- Automated Analysis of Tissue Microarrays -- Digital Microscopy for Boosting Database Integration and Analysis in TMA Studies -- From Gene to Clinic: TMA-Based Clinical Validation of Molecular Markers in Prostate Cancer.
520			_aToday's tissue microarray (TMA) method presents as a modern high-tech technology, one which allows for the linking of clinical data to the tissues that are combined on one slide. In Tissue Microarrays: Methods and Protocols, expert researchers explore the current world of TMA making and TMA applications, providing insight into the inherent and complex aspects of the most popular assays used for in-situ tissue analysis. Chapters examine the range of TMA techniques that allow for a large number of tissues to be included in one TMA, preserve the integrity of donor tissue blocks, and present a highly organized array pattern that allows for the reliable allocation of clinical data to individual tissue spots. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Contemporary and ground-breaking, Tissue Microarrays: Methods and Protocols serves as an essential handbook for pathologists, molecular biologists, researchers in the life sciences, as well as physicians, a reflection of the various applications of current TMA technology.
700	1		_aSimon, Ronald _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781607618058
776	0	8	_iPrinted edition: _z9781607618072
776	0	8	_iPrinted edition: _z9781493961030
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-806-5 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2010
999			_c234534 _d234534