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008			100301s2005 xxu| s |||| 0|eng d
020			_a9781592599431
024	7		_a10.1385/1592599435 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aAntifungal Agents _cedited by Erika J. Ernst.
250			_a1st edition 2005
264		1	_aTotowa, NJ _bHumana Press _c2005
300			_a1 recurso en línea (X, 210 páginas) _b30 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Medicine _x1940-6037 _v118
505	0		_aSusceptibility Testing Methods of Antifungal Agents -- Antifungal Resistance -- Deoxyribonucleic Acid Fingerprinting Methods for Candida Species -- CARE-2 Fingerprinting of Candida albicans Isolates -- Targeted Gene Deletion in Candida albicans Wild-Type Strains by MPA R Flipping -- Application of Deoxyribonucleic Acid Microarray Analysis to the Study of Azole Antifungal Resistance in Candida albicans -- Application of Proteomic Analysis to the Study of Azole Antifungal Resistance in Candida albicans -- Techniques for Antifungal Susceptibility Testing of Candida albicans Biofilms -- Antifungal Development and Evaluation -- Natural Products and Antifungal Drug Discovery -- Use of an Animal Model of Disseminated Candidiasis in the Evaluation of Antifungal Therapy -- Murine Model of Invasive Aspergillosis -- Antifungal Combinations -- Postantifungal Effect Methods -- Host Responses and Immunotherapy -- Evaluation of Immunotherapy in Invasive Candidiasis -- Interaction of Histoplasma capsulatum With Human Macrophages, Dendritic Cells, and Neutrophils -- Immunology of Infection Caused by Cryptococcus neoformans.
520			_aWith the growing frequency of fungal infections even as resistance to existing antifungal agents increases, methods for finding novel drug targets and evaluating antifungal resistance have become more important than ever. In Antifungal Agents: Methods and Protocols, expert scientists describe in detail the state-of-the-art molecular methods they have optimized for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents. Many of the protocols were developed in the laboratory and, when a method is limited to specific organisms, include alternative techniques to expand their application. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Antifungal Agents: Methods and Protocols offers clinician-scientists, microbiologists, and molecular biologists the productive tools they need today in order to understand and successfully develop new therapeutic agents for yeast, mold, and fungal infections.
700	1		_aErnst, Erika J _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781617374678
776	0	8	_iPrinted edition: _z9781588292773
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592599435 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2005
999			_c234634 _d234634