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001			234668
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007			cr nn 008mamaa
008			150122s2015 xxu| s |||| 0|eng d
020			_a9781493922505
024	7		_a10.1007/978-1-4939-2250-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aOrganism Models of Autism Spectrum Disorders _cedited by Pierre L. Roubertoux.
250			_a1st edition 2015
264		1	_aNew York, NY _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XVIII, 487 páginas) _b98 ilustraciones, 27 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v100
505	0		_aOrganism Models: Choosing the Right Model -- The Autistic Spectrum Disorders (ASD) : From the Clinics to the Molecular Analysis -- Selecting the Right Species: Practical Information on Organism Models -- Viewing Animal Models for Tuberous Sclerosis Complex in the Light of Evolution -- In Vivo Imaging in Mice -- Invertebrate Models of Synaptic Transmission in Autism Spectrum Disorders -- Epigenetic Factors in Normal and Pathological Neuronal Development -- Finding Endophenotypes for Autism Spectrum Disorders (ASD): cDNA Microarrays and Brain Transcripts -- Serotonin Disturbance in Mouse Models of Autism Spectrum Disorders -- Communication and Language in Animals -- Social Relationships in Nonhuman Primates: Potential Models of Pervasive Disorders -- Zebrafish Social Behaviour Testing in Developmental Brain Disorders -- Maintaining Mice for Neurobehavioral Examination -- Deficit in Social Relationships and Reduced Field of Interest in Mice -- Modeling Autism Spectrum Disorders Motor Deficits in Mice -- Neuro-Behavioral Testing of Mouse Models of Rett Syndrome -- Mouse Models of Tuberous Sclerosis -- Use of the Zebrafish Model to Understand Behavioral Disorders Associated with Altered Oxytocin System Development: Implications for Autism and Prader-Willi Syndrome -- Epilogue: Perspectives and Caveats.
520			_aAs autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab. Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.
700	1		_aRoubertoux, Pierre L _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9781493922499
776	0	8	_iPrinted edition: _z9781493922512
776	0	8	_iPrinted edition: _z9781493942190
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2250-5 _z(usuarios Universidad Europea de Valencia)
942			_2lcc _cLE
988			_aSpringer_Protocols_2015
999			_c234668 _d234668