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020 _a9781493970278
024 7 _a10.1007/978-1-4939-7027-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aBiological Networks and Pathway Analysis
_cedited by Tatiana V. Tatarinova, Yuri Nikolsky.
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XIV, 509 páginas)
_b110 ilustraciones, 98 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1613
505 0 _aA Practical Guide to Quantitative Interactor Screening with Next-Generation Sequencing (QIS-Seq) -- sbv IMPROVER: Modern Approach to Systems Biology -- Mathematical Justification of Expression-Based Pathway Activation Scoring (PAS) -- Bioinformatics Meets Biomedicine: OncoFinder, a Quantitative Approach for Interrogating Molecular Pathways Using Gene Expression Data -- Strategic Integration of Multiple Bioinformatics Resources for System Level Analysis of Biological Networks -- Functional Analysis of OMICs Data and Small Molecule Compounds in an Integrated "Knowledge-Based" Platform -- Extracting the Strongest Signals from Omics Data: Differentially Expressed Pathways and Beyond -- Search for Master Regulators in Walking Cancer Pathways -- Mathematical Modeling of Avidity Distribution and Estimating General Binding Properties of Transcription Factors from Genome-Wide Binding Profiles -- A Weighted SNP Correlation Network Method for Estimating Polygenic Risk Scores -- Analysis of cis-Regulatory Elements in Gene Co-Expression Networks in Cancer -- Applying Association Rule Mining Techniquest to Predict Procaryotic Metabolic Pathways -- ArrayTrack: An FDA and Public Genomic Tool -- Identification of Transcriptional Regulators of Psoriasis from RNA-Seq Experiments -- Comprehensive Analyses of Tissue-Specific Networks with Implications to Psychiatric Diseases -- Semantic Data Integration and Knowledge Management to Represent Biological Network Associations -- Knowledge-Based Compact Disease Models: A Rapid Path from High-Throughput Data to Understanding Causative Mechanisms for a Complex Disease -- Pharmacologic Manipulation of Wnt Signaling and Cancer Stem Cells -- Functional Network Disruptions in Schizophrenia.
520 _aIn this volume, expert practitioners present a compilation of methods of functional data analysis (often referred to as "systems biology") and its applications in drug discovery, medicine, and basic disease research. It covers such important issues as the elucidation of protein, compound and gene interactions, as well as analytical tools, including networks, interactome and ontologies, and clinical applications of functional analysis. As a volume in the highly successful Methods in Molecular Biology series, this work provides detailed description and hands-on implementation advice. Reputable, comprehensive, and cutting-edge, Biological Networks and Pathway Analysis presents both "wet lab" experimental methods and computational tools in order to cover a broad spectrum of issues in this fascinating new field.
700 1 _aTatarinova, Tatiana V
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aNikolsky, Yuri
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9781493970254
776 0 8 _iPrinted edition:
_z9781493970261
776 0 8 _iPrinted edition:
_z9781493983728
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7027-8
_z(usuarios Universidad Europea de Valencia)
942 _2lcc
_cLE
988 _aSpringer_Protocols_2017
999 _c234736
_d234736